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Models

About 80 results
Mice

Ldlr-KO(2)

Strain Name：C57BL/6Smoc-Ldlrem1Smoc
Strain State：Repository Live | Cat. NO.：NM-KO-210198
Validation Data：Presence

Ldlr-KO(2) mice(Stock No.NM-KO-210198) carry a knockout allele derived from the targeted deletion of exon 4. While Ldlr-KO mice(Stock No.NM-KO-190559) carrying the exon 6-10 deletion.

Mice

Fgf21-Flox

Strain Name：B6;129S-Fgf21tm1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-CKO-00136

These mice carry loxP sites flanking exon 1-2 of Fgf21 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Fgf21 gene.While Fgf21-Flox(2)(Stock No.NM-CKO-200176）mice carrying the loxP sites flanking exon 1-3 of Fgf21 gene.

Mice

Fgf21-Flox(2)

Strain Name：C57BL/6Smoc-Fgf21em1(flox)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-CKO-200176

These mice carry loxP sites flanking exon 1-3 of Fgf21 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Fgf21 gene.While Fgf21-Flox(Stock No.NM-CKO-00136)mice carrying the loxP sites flanking exon 1-2 of Fgf21 gene.

Mice

Sirt1-Flox

Strain Name：C57BL/6Smoc-Sirt1tm1(flox)Smoc
Strain State：Repository Live | Cat. NO.：NM-CKO-190037

These mice carry loxP sites flanking exon3 of Sirt1 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Sirt1 gene.

Mice

Sirt3-Flox

Strain Name：C57BL/6Smoc-Sirt3tm1(flox)Smoc
Strain State：Repository Live | Cat. NO.：NM-CKO-190039

These mice carry loxP sites flanking exon4 of Sirt3 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Sirt3 gene.

Mice

Lep-KO

Strain Name：B6;129S-Leptm1Smoc
Strain State：Repository Live | Cat. NO.：NM-KO-00034
Validation Data：Presence

Exon 2 was replaced by Neo cassette.

Mice

Ucp2-KO

Strain Name：B6;129S-Ucp2tm1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-00038

Homozygous null mutants may have elevated pancreatic islet cell ATP levels and increased glucose-stimulated secretion of insulin.

Mice

B6 DIO

Strain Name：C57BL/6Smoc DIO
Strain State：Repository Live | Cat. NO.：SM-021

Diet-induced obesity (DIO) models are similar to human obesity, can effectively reflect the pathogenesis of human obesity, and are useful for studying metabolic diseases such as obesity, diabetes, and fatty liver disease.

Mice

Abtb1-KO

Strain Name：B6;129S-Abtb1tm1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-00001

Exon 2 to exon 12 were replaced with Neo cassette.

Mice

Gchfr-KO

Strain Name：C57BL/6Smoc-Gchfrem1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-190961

Exon 2 of Gchfr gene was deleted to generate Gchfr knockout mice.

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