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Models

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Mice

Sry-KO

Strain Name：C57BL/6Smoc-Sryem1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-190152

This Sry knockout mouse model was generated by knocking out the exon 1 region of the Sry.

Mice

Pjvk-KO

Strain Name：C57BL/6Smoc-Pjvkem1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-191213

This Pjvk knockout mouse model was generated by deleting the exon 2 region of the Pjvk.

Mice

Zic2-KO

Strain Name：C57BL/6Smoc-Zic2em1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-00082

This Zic2 gene knockout mouse model is generated by TALEN technology.

Mice

MHC Class II (I-A/I-E) -KO

Strain Name：C57BL/6Smoc-H2-Ab1em1H2-Aaem1 H2-Eb1em1H2-Eb2em1H2-Ea-ps em1 Smoc
Strain State：Repository Live | Cat. NO.：NM-KO-18032
Validation Data：Presence

All sequences from the upstream of mouse H2-Ab1 gene exon 2 to the upstream of the H2-Ea-ps gene exon 1 were knocked out to obtain H2-Ab1、H2-Aa、H2-Eb1、H2-Eb2、H2-Ea-ps knockout mouse models. These MHC class II molecule-deficient mice were on the C57BL/6J genetic background and also lacked cell surface expression of both class II-A and class II-E MHC proteins.

Mice

MHC ClassII(I-A/I-E)-KO(NMG)

Strain Name：NOD.Cg-PrkdcscidIl2rgem1H2-Ab1em1H2-Aaem1H2-Eb1em1H2-Eb2em1H2-Ea-ps em1Smoc
Strain State：Developing | Cat. NO.：NM-NSG-003

All sequences from the upstream of mouse H2-Ab1 gene exon 2 to the upstream of the H2-Ea-ps gene exon 1 were knocked out to obtain H2-Ab1、H2-Aa、H2-Eb1、H2-Eb2、H2-Ea-ps knockout mouse models. These MHC class II molecule-deficient mice were on the NMG genetic background and also lacked cell surface expression of both class II-A and class II-E MHC proteins.

Mice

MHC Class II(I-A/I-E)-KO(Nod-Scid)

Strain Name：NOD-PrkdcscidH2-Ab1em1H2-Aaem1H2-Eb1em1H2-Eb2em1H2-Ea-psem1Smoc
Strain State：Developing | Cat. NO.：NM-KO-18057

All sequences from the upstream of mouse H2-Ab1 gene exon 2 to the upstream of the H2-Ea-ps gene exon 1 were knocked out to obtain H2-Ab1、H2-Aa、H2-Eb1、H2-Eb2、H2-Ea-ps knockout mouse models. These MHC class II molecule-deficient mice were on the Nod-Scid genetic background and lacked cell surface expression of both class II-A and class II-E MHC proteins.

Mice

Lhfpl6-KO

Strain Name：C57BL/6Smoc-Lhfpem1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-231353

The exon2 of gene was deleted to generate knockout mouse.

Mice

2310034G01Rik-KO

Strain Name：C57BL/6Smoc-em1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-232122

The exon 2 of gene was deleted to generate knockout mouse.

Mice

Ptger4-KO

Strain Name：C57BL/6Smoc-Ptger4em1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-231354

The exon2 of Ptger4 gene was deleted to generate knockout mouse.

Mice

Tph1-KO(2)

Strain Name：C57BL/6Smoc-Tph1em2Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-231220

The exon4 of Tph1 gene was deleted to generate Tph1 knockout mouse.

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