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Models

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Mice

hCD40L(BALB/c)

Strain Name：BALB/cAnSmoc-Cd40lgtm1(hCD40L)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000052

The endogenous mouse Cd40lg gene was replaced by human CD40L gene.

Mice

hIL4/hIL4R

Strain Name：C57BL/6Smoc-Il4tm3(hIL4)Il4ratm1(hIL4R)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-2000106
Validation Data：Presence

These mice are obtained through breeding of two single gene humanized mice.

Mice

hSIGLEC15(BALB/c)

Strain Name：BALB/cAnSmoc-Siglec15tm2(hSIGLEC15) Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-200001
Validation Data：Presence

The endogenous mouse Siglec15 gene was replaced by human SIGLEC15 gene .

Mice

hMASP2

Strain Name：C57BL/6Smoc-Masp2tm1(hMASP2)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000076
Validation Data：Presence

The endogenous mouse Masp2 gene was replaced by human MASP2 gene.

Mice

hFCGR2A

Strain Name：C57BL/6Smoc-Fcgr2btm3(hFCGR2A)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000071
Validation Data：Presence

The endogenous mouse Fcgr2b gene was replaced by human FCGR2A gene.

Mice

hPD-L1/hVISTA

Strain Name：C57BL/6Smoc-Visrtm1(hVSIR)Cd274tm1(hCD274)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000094

hPD-L1(NM-HU-00062) was crossed with hVISTA(NM-HU-00118) to generate hPD-L1/hVISTA.

Mice

hPD-L2(BALB/c)

Strain Name：BALB/cAnSmoc-Pdcd1lg2tm1(hPDCD1LG2)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-190061

The endogenous mouse Pdcd1lg2 gene was replaced by human PDCD1LG2 gene.

Mice

hPD-L1/hVEGFR2

Strain Name：C57BL/6Smoc-Cd274tm1(hCD274)Kdrtm2(hKDR)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000102

hPD-L1(NM-HU-00062) was crossed with hKDR(NM-HU-00098) to generate hPD-L1/hKDR.

Mice

hCD96

Strain Name：C57BL/6Smoc-Cd96tm2(hCD96)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000059
Validation Data：Presence

The endogenous mouse Cd96 gene was replaced by human CD96 gene.

Mice

hPD-L1(E3-4)

Strain Name：C57BL/6Smoc-Cd274tm2(hPD-L1)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-190039
Validation Data：Presence

Extracellular domain of mouse Cd274(also known as PD-L1) gene was replaced by human PD-L1 gene. While hPD-L1(Stock No.NM-HU-00062) mice function similarly to hPD-L1(2) mice,for more detailed information please contact our technical advisor.

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