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Mice

hPD-1/hCTLA-4

Strain Name:C57BL/6Smoc-Pdcd1tm1(hPDCD1)Ctla4tm1(hCTLA4)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-00079
Validation Data:Presence

hPD-1(NM-HU-00015) was crossed with hCTLA4(NM-HU-00014)to generate hPD-1/hCTLA4 mice

Mice

hOX40(2)

Strain Name:C57BL/6Smoc-Tnfrsf4tm3(hTNFRSF4) Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-00078
Validation Data:Presence

The exon1-5 and partial exon6 of endogenous mouse Tnfrsf4(Ox40) gene was replaced by the corresponding region of human TNFRSF4(OX40) gene. While hOX40(Stock No.NM-HU-00041) mice function similarly to hOX40(2) mice,for more detailed information please contact our technical advisor.

Mice

hPD-1/hPD-L1/hIDO1

Strain Name:C57BL/6Smoc-Ido1tm1(hIDO1)Pdcd1tm1(hPDCD1)Cd274tm1(hPD-L1)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-00120

hPD-1(NM-HU-00015),hPD-L1(NM-HU-00062) were crossed with hIDO1(NM-HU-00061) to generate hPD-1/hPD-L1/hIDO1.

Mice

hPD-L1/hOX40

Strain Name:C57BL/6Smoc-Cd274tm1(hPD-L1)Tnfrsf4tm1(hTNFRSF4)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-00111

hPD-L1(NM-HU-00062)was crossed with hOX40(NM-HU-00041)to generate hPD-L1/hOX40.

Mice

hPD-1/hOX40

Strain Name:C57BL/6Smoc-Pdcd1tm1(hPDCD1)Tnfrsf4tm3(hTNFRSF4) Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-00108

hPD-1(NM-HU-00015)was crossed with hOX40(NM-HU-00041)to generate hPD-1/hOX40.

Mice

R26-CAG-hFcRn

Strain Name:C57BL/6Smoc-Gt(ROSA)26Sortm1(CAG-hFcRn)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KI-00081

A human FCGRT expression cassette was knocked in mouse Rosa26 loci.

Rats

hFcRn(SD)

Strain Name:SD-Fcgrtem1(hFCGRT)Smoc Strain State:Repository Live | Cat. NO.:NR-HU-200002
Validation Data:Presence

The endogenous rat Fcgrt gene was replaced by human FCGRT gene.

Literature
Literature

An oncolytic virus–T cell chimera for cancer immunotherapy

Model Organisms:小鼠 Product & Service:- Research field:

Literature

Ultrasound Control of Genomic Regulatory Toolboxes for Cancer Immunotherapy

Model Organisms:小鼠 Product & Service:- Research field:

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