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Models

About 199 results
Mice

hTIGIT/hPVR

Strain Name:C57BL/6Smoc-Tigitem1(hTIGIT)Pvrem1(hPVR)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-2000091

These mice are obtained through breeding of two single gene humanized mice.

Mice

hLAIR1

Strain Name:C57BL/6Smoc-Lair1em2(LAIR1)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-2000011

The endogenous mouse Lair1 gene was replaced by human LAIR1 gene .

Mice

hPD-L1/hSIRPA(2)

Strain Name:C57BL/6Smoc-Sirpatm2(hSIRPA)Cd274em1(hCD274)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-2000099

hPD-L1(NM-HU-00062) was crossed with hSIRPA(2)(NM-HU-18015) to generate hPD-L1/hSIRPA(2).

Mice

hIL4

Strain Name:C57BL/6Smoc-Il4tm3(hIL4)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-190071

The endogenous mouse Il4 gene was completely or partially replaced by human IL4 gene via ESC targeting.

Mice

hPD-1/hCD27(2)

Strain Name:C57BL/6Smoc-Pdcd1em1(hPDCD1)Cd27tm2(hCD27)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-2000096

hPD-1(NM-HU-00015) was crossed with hCD27(2)(NM-HU-190035) to generate hPD-1/hCD27(2).

Mice

hICOS(BALB/c)

Strain Name:BALB/cAnSmoc-Icosem1(hICOS)/Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-HU-2000046

The endogenous mouse Icos gene was replaced by human ICOS gene.

Mice

hCD4(BALB/c)

Strain Name:BALB/cAnSmoc-Cd4em3(hCD4)/Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-2000053

The endogenous mouse Cd4 gene was replaced by human CD4 gene.

Mice

hFCGR1A

Strain Name:C57BL/6Smoc-Fcgr1tm3(hFCGR1A)/Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-2000072

The endogenous mouse Fcgr1 gene was replaced by human FCGR1A gene.

Mice

hIL6

Strain Name:C57BL/6Smoc-Il6tm1(hIL6)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-18017

This IL6 humanized mouse model was established by replacing the mouse Il6 gene coding exon1-5 and introns with the human IL6 corresponding sequence by homologous recombination via ES cell targeting.

Mice

hTLR7/hTLR8

Strain Name:C57BL/6Smoc-Tlr7tm3(hTLR7)Tlr8tm3(hTLR8)/Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-2000015

The endogenous mouse Tlr7 and Tlr8 gene was replaced by human TLR7 and TLR8 gene.

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