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Models

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Mice

hPD-L1/hSIGLEC15

Strain Name:C57BL/6Smoc-Cd274tm1(hCD274)Siglec15tm1(hSIGLEC15)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-2000103

hPD-L1(NM-HU-00062) was crossed with hSIGLEC15(NM-HU-190037) to generate hPD-L1/hSIGLEC15.

Mice

hSIGLEC10

Strain Name:C57BL/6Smoc-Siglecgtm1(hSIGLEC10)/Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-2000061
Validation Data:Presence

The endogenous mouse Siglecg gene was replaced by human SIGLEC10 gene.

Mice

hPD-1/hSEMA4D

Strain Name:C57BL/6Smoc-Pdcd1tm1(hPDCD1)Sema4dtm1(hSemA4D)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-190033

hPD-1(NM-HU-00015) was crossed with hSEMA4D(NM-HU-00117) to generate hPD-1/hSEMA4D.

Mice

hPD-1/hVISTA

Strain Name:C57BL/6Smoc-Visrtm1(hVSIR)Pdcd1tm1(hPDCD1)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-2000092

hPD-1(NM-HU-00015) was crossed with hSIRPA(2) (NM-HU-18015) to generate hPD-1/hVISTA.

Mice

hMARCO

Strain Name:C57BL/6Smoc-Marcotm1(hMARCO)/Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-2000029
Validation Data:Presence

The endogenous mouse Marco gene was replaced by human MARCO gene.

Mice

hPD-1/hCD3E

Strain Name:C57BL/6Smoc-Pdcd1tm1(hPDCD1)Cd3etm1(hCD3E)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-18021

hPD-1(NM-HU-00015)was crossed with hCD3E(NM-HU-00114)to generate hPD-1/hCD3E。

Mice

hDLL4

Strain Name:C57BL/6Smoc-Dll4tm1(hDLL4)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-2000020
Validation Data:Presence

The endogenous mouse Dll4 gene was replaced by human DLL4 gene.

Mice

hCTLA-4(2)

Strain Name:C57BL/6Smoc-Ctla4tm2(hCTLA4)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-190038

Extracellular domain of mouse Ctla4 gene was replaced by human CTLA4 gene. While hCTLA4(Stock No.NM-HU-00014) mice function similarly to hCTLA4(2) mice,for more detailed information please contact our technical advisor.

Mice

hHGF(NMG)

Strain Name:NOD.Cg-PrkdcscidIl2rgem1Hgfem1(hHGF)Smoc
Strain State:Developing | Cat. NO.:NM-NSG-013

The endogenous mouse Hgf gene was replaced by human HGF gene. (NMG Background)

Mice

hICOSL(2)

Strain Name:C57BL/6Smoc-Icosltm3(hICOSLG)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-2000068
Validation Data:Presence

The endogenous mouse Icosl gene was replaced by human ICOSLG gene. While hICOSL(Stock No.NM-HU-00095) mice function similarly to hICOSL(2) mice,for more detailed information please contact our technical advisor.

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