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Models

About 199 results
Mice

hCTLA-4/hCD28(BALB/c)

Strain Name：BALB/cAnSmoc-Ctla4em1(hCTLA4)Cd28em1(hCD28)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-HU-200226

The endogenous mice Ctla4 and Cd28 gene was replaced by human CTLA4 and CD28 gene.

Mice

hOX40/hCTLA-4

Strain Name：C57BL/6Smoc-Tnfrsf4em3(hTNFRSF4)Ctla4em1(hCTLA4)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-00105

These mice are OX40 and CTLA4 double knockin mouse models which can be useful for evalueting the efficacy of potential immunotherapy drug combinations.

Mice

hICOS/hICOSL

Strain Name：C57BL/6Smoc-Icoslem1(hICOSLG) Icosem1(hICOS)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-18018

This ICOS and ICOSL double knockin strain is established by crossing ICOS-HU and ICOSL-HU mice together. These double double knockin mouse models can be useful for evalueting the efficacy of potential immunotherapy drug combinations.

Mice

hSIRPA(2)/hCD47

Strain Name：C57BL/6Smoc-Sirpatm2(hSIRPA)Cd47em1(hCD47)/Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-2000111

This SIRPA and CD47 double Knock-in strain is established by crossing hSIRPA and hCD47 mice together. These double double Knock-in mouse models can be useful for evalueting the efficacy of potential immunotherapy drug combinations.While hSIRPA/hCD47 (Stock No.NM-HU-190019) have been pulled from shelves for some reasons.

Mice

hCTLA-4/4-1BB

Strain Name：C57BL/6Smoc-Ctla4em1(hCTLA4) Tnfrsf9em1(hTNFRSF9) /Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-18020

This CTLA4 and 4-1BB double knockin strain is established by crossing CTLA4-HU and 4-1BB-HU mice together. These double double knockin mouse models can be useful for evalueting the efficacy of potential immunotherapy drug combinations.

Mice

NVG-hIL15

Strain Name：NOD.Cg-PrkdcscidIl2rgem1SmocIl15em1(hIL15)Smoc
Strain State：Repository Live | Cat. NO.：GM-NVG-210001

The endogenous mice Il15 gene was replaced by human IL15 gene.

Mice

hKITLG(NMG)

Strain Name：NOD-PrkdcscidIl2rgem1Kitlem1(hKITLG)/Smoc
Strain State：Developing | Cat. NO.：NM-HU-2000039

The endogenous mouse Kitl gene was replaced by human KITLG gene.

Mice

hFCGRT(NMG）

Strain Name：NOD-PrkdcscidIl2rgem1Fcgrtem2(FCGRT)Smoc
Strain State：Repository Live | Cat. NO.：NM-NSG-020

The background of this strain is NMG, and its endogenous Fcgrt gene is replaced with human FCGRT.

Mice

hHGF(NMG)

Strain Name：NOD-PrkdcscidIl2rgem1Hgfem1(hHGF)Smoc
Strain State：Developing | Cat. NO.：NM-NSG-013

The endogenous mouse Hgf gene was replaced by human HGF gene. (NMG Background)

Mice

hIL3(NMG)

Strain Name：NOD-PrkdcscidIl2rgem1Il3em4(hIL3)/Smoc
Strain State：Repository Live | Cat. NO.：NM-NSG-007

The endogenous mouse Il3 gene was replaced by human IL3 gene.

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