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Models

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Mice

hPD-1/hCD40

Strain Name：C57BL/6Smoc-Pdcd1em1(hPDCD1)Cd40em1(hCD40)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-190017

hPD-1(NM-HU-00015) was crossed with hCD40(NM-HU-00076) to generate hPD-1/hCD40.

Mice

Il33-KO(2)

Strain Name：C57BL/6Smoc-Il33em2Smoc
Strain State：Repository Live | Cat. NO.：NM-KO-190436

Il33-KO(2) mice(Stock No.NM-KO-190436) carry a knockout allele derived from the targeted deletion of exon 3-7. While Il33-KO mice(Stock No.NM-KO-00099) have been pulled from shelves for some reasons and Il33-KO(3) mice(Stock No.NM-KO-210206) carrying the exon 2 deletion.

Mice

hKLRK1

Strain Name：C57BL/6Smoc-Klrk1em1(hKLRK1)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-190005

The endogenous mouse Klrk1 gene was replaced by human KLRK1 gene.

Mice

hPD-1/hPD-L1/hLAG3

Strain Name：C57BL/6Smoc-Pdcd1em1(hPDCD1)Cd274em1(hPD-L1)Lag3em1(hLAG3)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-190028

hPD-1(NM-HU-00015),hPD-L1(NM-HU-00062) were crossed with hLAG3(NM-HU-00049) to generate hPD-1/hPD-L1/hLAG3.

Mice

H2-DMa-KO

Strain Name：C57BL/6Smoc-H2-DMaem1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-190816

Exon 2-4 of H2-DMa gene was deleted to generate H2-DMa knockout mice.

Mice

Snca-KO

Strain Name：C57BL/6Smoc-Sncaem1Smoc
Strain State：Repository Live | Cat. NO.：NM-KO-190380

This Snca knockout mouse model was generated by knocking out the exon4 region of the Snca.

Mice

Fas-KO(BALB/c)

Strain Name：BALB/cAnSmoc-Fasem2Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-191206

Exon 2 of Fas gene was deleted to generate Fas knockout mice.

Mice

Prkn-KO

Strain Name：C57BL/6Smoc-Prknem1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-190335

Prkn-KO mice (Stock No.NM-KO-190335）carry a knockout allele derived from the targeted deletion of exon 3. While Prkn-KO(2) mice (Stock No.NM-KO-191005）mice carrying the exon 4 deletion.

Mice

hPD-1/hTIGIT/hTIM3

Strain Name：C57BL/6Smoc-Pdcd1em1(hPDCD1)Tigitem1(hTIGIT) Havcr2em1(hHAVCR2)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-190029

hPD-1(NM-HU-00015),hTIGIT(NM-HU-00053) were crossed with hTIM3(NM-HU-00054) to generate hPD-1/hTIGIT/hTIM3.

Mice

Sirt3-KO

Strain Name：C57BL/6Smoc-Sirt3em1Smoc
Strain State：Repository Live | Cat. NO.：NM-KO-190368

This Sirt3 knockout mouse model was generated by knocking out the exon 2-3 region of the Sirt3.

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