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Models

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Mice

Cd274-KO(2)

Strain Name:C57BL/6Smoc-Cd274em2Smoc
Strain State:Repository Live | Cat. NO.:NM-KO-18044

Cd274 gene is also called B7-H1, Pdcd1lg1 or PD-L1. The PD-L1-KO(2) mouse model was obtained by deleting the Exon 3-5 region of mouse Cd274 gene. While PD-L1-KO(Stock No.NM-KO-00104) mice have been pulled from shelves for some reasons.

Mice

hTLR9

Strain Name:C57BL/6Smoc-Tlr9tm1(hTLR9)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-18016

This TLR9 humanized mouse model was established by replacing the mouse Tlr9 gene exon2 with the human TLR9 corresponding sequence by homologous recombination.

Mice

Ccr6-KO

Strain Name:C57BL/6Smoc-Ccr6em1Smoc
Strain State:Repository Live | Cat. NO.:NM-KO-190022

This Ccr6 knockout mouse model was generated by knocking out the exon 3 region of the Ccr6.

Mice

Ccl19-KO

Strain Name:C57BL/6Smoc-Ccl19em1Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KO-190011

This Ccl19 knockout mouse model was generated by knocking out the exon 2-4 region of the Ccl19 .

Mice

Cd4-KO(2)

Strain Name:C57BL/6Smoc-Cd4em3Smoc
Strain State:Repository Live | Cat. NO.:NM-KO-190441

Cd4-KO(2) mice (Stock No.NM-KO-190441) carry a knockout allele derived from the targeted deletion of exon 3-8. While Cd4-KO mice (Stock No.NM-KO-18023) have been pulled from shelves for some reasons.

Mice

Il17a-2A-CreERT2

Strain Name:C57BL/6Smoc-Il17aem1(2A-CreERT2)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KI-00059

A 2A-Cre cassette was inserted before stop codon of mouse Il17a gene which is known as a T cell marker.

Mice

Foxn1-KO

Strain Name:B6;129S-Foxn1tm1Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KO-00052

Exons 1-4 were replaced by Neo cassette.

Mice

Tgfb1-Flox

Strain Name:B6;129S-Tgfb1tm1(flox)Smoc
Strain State:Repository Live | Cat. NO.:NM-CKO-00107

These mice harbor loxP sites flanking exon 2 of the Tgfb1 (transforming growth factor, beta 1) gene.

Mice

Aimp1-Flox

Strain Name:B6;129S-Aimp1tm1(flox)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-CKO-00064

These mice carry loxP sites flanking exon 2. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of the gene.

Mice

Il1f6-KO

Strain Name:C57BL/6Smoc-Il1f6em1Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KO-00097

Exon2-3 of Il1f6 gene were targeted to generate Il1f6 knockout mice.

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