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Models

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Mice

C57BL/6

Strain Name：C57BL/6Smoc
Strain State：Repository Live | Cat. NO.：SM-001

C57BL/6 mice have a high reproductive capacity, a long life span, and a low tumor susceptibility. Male mice are aggressive and fight frequently. Diet can cause obesity, type II diabetes, and atherosclerosis in these mice. The C57BL/6 mouse is the first to have its entire genome sequenced. It is the most extensively used inbred mouse strain as a genetic basis for congenic and mutant mice. It is also used in genetics, metabolism, immunology, neurology, behavioral research, pharmacodynamics, and medication safety evaluation.

Mice

R26-CAG-LSL-GiDREADD(hM4Di)-2A-mCitrine

Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-LSL-HA-GiDREADD(hM4Di)-2A-mCitrine-WPRE-pA)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-190093

These mice harbor a CAG-LSL-HA-GiDREADD(hM4Di)-2A-mCitrine-WPRE-pA cassette in the Rosa26 locus generated by homologous recombination.

Mice

R26-CAG-LSL-GqDREADD(hM3Dq)-2A-mCitrine

Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-LSL-HA-GqDREADD(hM3Dq)-P2A-mCitrine-WPRE-polyA)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-190106

These mice harbor a CAG-LSL-HA-GiDREADD（hM3Dq)-P2A-mCitrine-WPRE-polyA cassette in the Rosa26 locus generated by homologous recombination.

Mice

Bhlhe40-KO

Strain Name：C57BL/6Smoc-Bhlhe40em1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-191085

Exon 2 of Bhlhe40 gene was deleted to generate Bhlhe40 knockout mice. While Bhlhe40-KO(2) mice (Stock No.NM-KO-210446）carrying the Exon 1-4 deletion.

Mice

MHC Class II (I-A/I-E) -KO

Strain Name：C57BL/6Smoc-H2-Ab1em1H2-Aaem1 H2-Eb1em1H2-Eb2em1H2-Ea-ps em1 Smoc
Strain State：Repository Live | Cat. NO.：NM-KO-18032

All sequences from the upstream of mouse H2-Ab1 gene exon 2 to the upstream of the H2-Ea-ps gene exon 1 were knocked out to obtain H2-Ab1、H2-Aa、H2-Eb1、H2-Eb2、H2-Ea-ps knockout mouse models. These MHC class II molecule-deficient mice were on the C57BL/6J genetic background and also lacked cell surface expression of both class II-A and class II-E MHC proteins.

Mice

Slc6a1-S295L

Strain Name：C57BL/6Smoc-Slc6a1em2(S295L)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-190014

These mice carry a p.S295L mutation in Slc6a1 gene .

Mice

Cacna1a-KO(2)

Strain Name：C57BL/6Smoc-Cacna1aem1Smoc
Strain State：Developing | Cat. NO.：NM-KO-242505

The exon 3 of Cacna1a gene was deleted to generate Cacna1a knockout mouse.There have been reports of deaths caused by genetic modification. For details, click on the MGI ID in the genetic information.

Mice

hTSLP(NMG)

Strain Name：NOD-PrkdcscidIl2rgem1Tslptm(hTSLP)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-220426

The hTSLP(NM-HU-2000064) mice were backcrossed to NMG genetic background, to create the new strain of hTSLP(NMG) (NM-HU-220426) mice.

Mice

hTHPO(NMG)

Strain Name：NOD-PrkdcscidIl2rgem1Thpotm(hTHPO)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-220429

The hTHPO(NM-HU-2000062) mice were backcrossed to NMG genetic background, to create the new strain of hTHPO(NMG) (NM-HU-220429) mice.

Mice

hIL2(NMG,2)

Strain Name：NOD-PrkdcscidIl2rgem1Il2tm(hIL2)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-220425

The hIL2 (NM-HU-190048) mice were backcrossed to NMG genetic background, to create the new strain of hIL2(NMG) (NM-HU-220425) mice.

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