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Literature

A genetic system for tissue-specific inhibition of cell proliferation

Model Organisms:Mouse Product & Service:Col1a2-CreER, R26-p21-GFP, R26-rox-p21-GFP Research field: cell lineages

Literature

Seamless Genetic Recording of Transiently Activated Mesenchymal Gene Expression in Endothelial Cells During Cardiac...

Model Organisms:小鼠 Product & Service:αSMA-LSL-Dre, Zeb1-LSL-Dre, and R26-CreER Research field:Heart

Literature

Dual Genetic Lineage Tracing Reveals Capillary to Artery Formation in the Adult Heart

Model Organisms:大鼠 Product & Service:Cdh5-DreER,Apln-CrexER,Cx40-LSL-GFP Research field:Developmental and Differentiation

Literature

Comparative population genomics reveals genetic basis underlying body size of domestic chickens

Model Organisms:斑马鱼 Product & Service:BMP10 Research field:Development

bmp10

Literature

Enhancing the precision of genetic lineage tracing using dual recombinases

Model Organisms:小鼠 Product & Service:IR1, IR2, NR1, NR2, CAG-DreER, Tnni3-Dre, Tnnt2-Dre, Alb-CreER, CK19-Dre 和 Alb-DreER Research field:Genetic lineage tracing

谱系示踪 DeaLT-IR 双报告基因系统

Literature

Generation of a self‐cleaved inducible Cre recombinase for efficient temporal genetic manipulation

Model Organisms:Mouse Product & Service:Npr3-sCreER, Npr3-CreER, Col1a2-sCreER, Col1a2-CreER, and R26-LZLT Research field:cell lineages

Literature

A Suite of New Dre-recombinase Drivers Markedly Expands the Ability to Perform Intersectional Genetic Targeting

Model Organisms:Mouse Product & Service:Sox9-IRES-DreERT2;Pdgfb-(DreERT2-IRES-eGFP-wpre-polyA) Research field:lineage tracing

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Harnessing the Power of the Cre-loxP System: Benefits, Challenges, and Applications

This webinar will introduce the Cre-loxP system, a powerful genetic tool that has revolutionized biological research by allowing for conditional gene knockout, knockdown, and overexpression. We will cover the history of the genetic recombination systems, discuss how they enable precise control of gene expression in specific cell types or at specific developmental stages, and present GenoBioTX’s genetically modified models utilizing this method.

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Join Our Webinar: Advanced Strategies in Genetically Modified Mice

Discover cutting-edge strategies and applications of genetically modified mice in biomedical research at our webinar on May 23rd, 2024. Register now for insights from industry expert Dongxiao Feng

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On Nature Genetics Prof. Bin Zhou's group used lineage-tracing mice produced by SMOC to investigate the role of bronchioalveolar stem cells

bronchioalveolar stem cells lung repair lung regeneration

Published on today's Nature Genetics, Prof. Bin Zhou's research group from Shanghai Institute of Biochemistry and Cell Biology revealed the bona fide role of bronchioalveolar stem cells (BASC) during lung repair and regeneration.

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