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Models

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Mice

H11-CAG-RSR-EYFP

Strain Name：C57BL/6Smoc-Igs2em1(CAG-RSR-EYFP)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-18056

A CAG-ROX-STOP-ROX-EYFP-V5tag-polyA conditional expression cassette was knocked into the Igs2 locus (Hipp11 or H11; an intergenic region on chromosome 11 [cytoband A1 at ~3cM between the Eif4enif1 and Drg1 loci] reported to support high-level global gene expression in conjunction with the CAG (CAGGS) promoter and a higher rate of mitotic/interchromosomal recombination compared to Gt(ROSA)26Sor) . This strain of mice can be used to mate with mice expressing the Dre recombinase. After exposure to Dre recombinase, expression of ellow fluorescent protein and V5 tag is observed for cell tracking.

Mice

Il1b-Luc-2A-EGFP

Strain Name：C57BL/6Smoc-Il1bem1(Luc-eGFP)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-00010

A Luciferase-2A-EGFP-pA cassette was inserted at ATG site of mouse Il1b gene. The intrisic promoter drives the expression of reporter genes, which reflects the activity of Il1b.

Mice

H11-CAG-EGFP

Strain Name：C57BL/6Smoc-Igs2 em1(CAG-EGFP-pA)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-00066

These mice harbor a CAG promoter-driven EGFP report gene. The targeted mutation was inserted into the Hipp11(H11) locus by homologous recombination.

Mice

Il2-IRES-Venus-Luc

Strain Name：C57BL/6Smoc-Il2em1(Venus-Luci)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-18057

an IRES-Venus Luci cassette was inserted into the IL2 gene stop codon site.

Mice

Spag11a-Luc-EGFP

Strain Name：C57BL/6Smoc-Spag11aem1(Luc-EGFP)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-00071

A Luciferase-2a-egfp-polyA cassette was inserted at ATG site of Spag11a gene.

Mice

Cd8a-IRES-Luc-2A-EGFP

Strain Name：C57BL/6Smoc-Cd8aem1(V5-IRES-luci-2A-EGFP)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-18030

A V5-IRES-luci-2A-EGFP expression cassette was inserted before the stop codon TAA of mouse Cd8a gene to establish a multi-labeled knockin model with V5, luciferase and EGFP fluorescent protein.

Mice

Foxp3-V5-AviTag-IRES-Luc-2A-tdTomato

Strain Name：C57BL/6Smoc-Foxp3em1(V5-AviTag-IRES-luci-2A-tdTomato)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-18034

A V5-AviTag-IRES-luci-2A-tdTomato expression cassette was inserted before the stop codon TGA of mouse Foxp3 gene to establish a multi-labeled knockin model with V5, Avi, luciferase and tdTomato fluorescent protein.

Mice

Tnf-HiBiT

Strain Name：C57BL/6Smoc-Tnfem4(HiBiT)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-190123

A HiBiT expression cassette was knocked into the Tnf gene stop codon site via CRISPR/Cas mediated recombination.

Mice

Tnf-IRES-NanoLuc

Strain Name：C57BL/6Smoc-Tnfem3(IRES-NanoLuc)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-190122

A IRES-NanoLuc expression cassette was knocked into the Tnf gene stop codon site.

Mice

Tnf-IRES-Luc

Strain Name：C57BL/6Smoc-Tnfem4(IRES-Luciferase)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-200003

A IRES-Luciferase expression cassette was knocked into the Tnf gene stop codon site via CRISPR/Cas mediated recombination.

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