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Mice

Fos-IRES-Venus-Luc

Strain Name：C57BL/6Smoc-Fosem1(IRES-Venus-Luci)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-18044

An IRES-Venus-Luci expression cassette was knocked into the Fos gene stop codon site by homologous recombination.

Mice

Lyz2-CreERT2-IRES-EGFP

Strain Name：C57BL/6Smoc-Lyz2em2(CreERT2-IRES-EGFP)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-18047
Validation Data：Presence

A Kozak-CreERT2-IRES-EGFP expression cassette was knocked into the Lyz2 gene start codon site by homologous recombination.

Mice

Tert-CreERT2-2A-EGFP

Strain Name：C57BL/6Smoc-Tertem1(CreERT2-2A-GFP-WPRE-PA)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-18037
Validation Data：Presence

A CreERT2-2A-GFP-WPRE-PA expression cassette was knocked into the Telt gene start codon site by homologous recombination.

Mice

Sftpc-IRES-rtTA

Strain Name：C57BL/6Smoc-Sftpcem2(Avitag-IRES-V5-M2rtTA-WPRE-polyA)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-18043
Validation Data：Presence

An Avitag-IRES-V5-M2rtTA-WPRE-polyA expression cassette was knocked into the Sftpc gene stop codon site by homologous recombination.

Mice

R26-CAG-LSL-Cas9-IRES-Luc

Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-LSL-Cas9-IRES-Luciferase-pA)
Strain State：Repository Live | Cat. NO.：NM-KI-18002

These mice harbor a loxP-flanked STOP cassette preventing transcription of a CAG promoter-driven Cas9 gene followed by IRES-Luciferase coexpression cassette. The targeted mutation was inserted into the Rosa26 locus by homologous recombination.

Mice

Slco1c1-2A-CreERT2

Strain Name：C57BL/6Smoc-Slco1c1em1(2A-CreERT2)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200262
Validation Data：Presence

2A-CreERT2 expression cassette was knocked into the Slco1c1 gene stop codon site. Slco1c1 encodes a member of the organic anion transporter family. The encoded protein is a transmembrane receptor that mediates the sodium-independent uptake of thyroid hormones in brain tissues. This protein has particularly high affinity for the thyroid hormones thyroxine, tri-iodothyronine and reverse tri-iodothyronine. When Slco1c1-2A-CreERT2 mice are bred with mice containing loxP-flanked sequence, tamoxifen-inducible, Cre-mediated recombination will result in deletion of the floxed sequences in SLCO1C1 positive cells.

Mice

Mc4r-KO(2)

Strain Name：C57BL/6Smoc-Mc4rem2Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-205021

exon 1 of Mc4r gene was deleted to generate Mc4r knockout mice via CRISPR/Cas9 mediated recombination.

Mice

Tet2-KO

Strain Name：B6;129S-Tet2tm1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-00127

Exon3 of mouse Tet2 gene was replaced by frt-Pgk-Neo-polyA-frt cassette by homologous recombination.

Mice

Vwf-KO

Strain Name：C57BL/6Smoc-Vwfem1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-200739

Exon 6 of Vwf gene was deleted to generate Vwf knockout mice via CRISPR/Cas9 mediated recombination.

Mice

Nanos2-KO(ICR)

Strain Name：ICR-Nanos2em2Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-205005

exon 1 of Nanos2 gene was deleted to generate Nanos2 knockout mice via CRISPR/Cas9 mediated recombination.

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