Therapeutic Target-Humanized Mice
Cre/Dre-Driver Mice
Immunodeficient NMG Mice
Strain Name：C57BL/6Smoc-Duxem1Smoc Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-242098
The Gm19459 gene, Gm4981 gene, Duxf3 gene, Gm10807 gene and AW822073 gene were deleted to generate Dux gene cluster knockout mouse.
Strain Name：C57BL/6Smoc-Foxl1em1(2A-CreERT2)Smoc Strain State：Repository Live | Cat. NO.：NM-KI-00135 Validation Data：Presence
A 2A-CreERT2 coexpression cassette is inserted before the stop codon of mouse Foxl1 gene via homologous recombination to establish a Foxl1-CreERT2 recombinase tool stain. This strain can be used to knockout target gene inFoxl1+ cells after tamoxifen treatment when crossed with flox mice.
Strain Name：B6;129S-Sox9tm1(IRES-Flp)Smoc Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-00131
An IRES-Flp-polyA coexpression cassette is inserted at 3' terminal of mouse Sox9 gene via homologous recombination to establish a Sox9-Flp recombinase tool stain. This strain can be used to knockout target gene in Sox9+ cells when crossed with mice which carry frt sites flanking target gene.
Strain Name：C57BL/6Smoc-Tie1em1(2A-Cre)Smoc Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-18023
A 2A-Cre coexpression cassette is inserted befor the stop codon of mouse Tie1 gene via homologous recombination to establish a tamoxifen inducible Tie1-Cre tool stain. This strain can be used to knockout target gene in Tie1+ cells when crossed with mice which carry loxp sites flanking target gene.
Strain Name：C57BL/6Smoc-Aplnrem1(2A-DreERT2)Smoc Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-00132 Publications：1piece
A 2A-DreERT2-SV40polyA coexpression cassette is inserted befor the stop codon of mouse Aplnr gene via homologous recombination to establish a tamoxifen inducible Aplnr-DreERT2 tool stain. This strain can be used to knockout target gene in Aplnr+ cells after tamoxifen treatment when crossed with mice which carry rox sites flanking target gene.
Strain Name：C57BL/6Smoc-Cyp2e1em1(DreERT2)Smoc Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-18010
A 2A-DreERT2-wpre-polyA coexpression cassette is inserted before the stop codon of mouse Cyp2e1 gene via homologous recombination to establish a Cyp2e1-DreERT2 recombinase tool stain. This strain can be used to knockout target gene in Cyp2e1+ cells afte
Strain Name：C57BL/6Smoc-Zbtb46em1(2A-CreERT2-WPRE-pA)Smoc Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-18021 Validation Data：Presence
A 2A-CreERT2-WPRE-pA coexpression cassette is inserted befor the stop codon of mouse Zbtb46 gene via homologous recombination to establish a tamoxifen inducible Zbtb46-CreERT2 tool stain. This strain can be used to knockout target gene in Zbtb46+ cells after tamoxifen treatment when crossed with mice which carry loxp sites flanking target gene.
Strain Name：C57BL/6Smoc-Lyz2em1(2A-CreERT2-WPRE-pA)Smoc Strain State：Repository Live | Cat. NO.：NM-KI-18018 Validation Data：Presence
A 2A-CreERT2-WPRE-pA coexpression cassette is inserted befor the stop codon of mouse Lyz2 gene via homologous recombination to establish a tamoxifen inducible Lyz2-CreERT2 tool stain. This strain can be used to knockout target gene in Lyz2+ cells after tamoxifen treatment when crossed with mice which carry loxp sites flanking target gene.
Strain Name：C57BL/6Smoc-Cd2em1(2A-CreERT2-WPRE-pA)Smoc Strain State：Repository Live | Cat. NO.：NM-KI-18017 Validation Data：Presence
A 2A-CreERT2-WPRE-pA coexpression cassette is inserted befor the stop codon of mouse Cd2 gene via homologous recombination to establish a tamoxifen inducible Cd2-CreERT2 tool stain. This strain can be used to knockout target gene in T cells and B cells after tamoxifen treatment when crossed with mice which carry loxp sites flanking target gene.
Strain Name：C57BL/6Smoc-Drd1em1(2A-CreERT2-WPRE-pA)Smoc Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-18016 Validation Data：Presence
A 2A-CreERT2-WPRE-pA coexpression cassette is inserted befor the stop codon of mouse Drd1 gene via homologous recombination to establish a tamoxifen inducible Drd1-CreERT2 tool stain. This strain can be used to knockout target gene in Drd1+ cells after tamoxifen treatment when crossed with mice which carry loxp sites flanking target gene.
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