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Models

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Mice

hMAPT

Strain Name：C57BL/6Smoc-Mapttm1(hMAPT)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-200116

The endogenous mouse Mapt gene was replaced by human MAPT gene. While hMAPT(2)(Stock No.NM-HU-200257) mice function similarly to hMAPT mice,for more detailed information please contact our technical advisor.

Mice

hAPP

Strain Name：C57BL/6Smoc-Apptm(hAPP)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-220224

The endogenous mouse APP gene was replaced by human APP gene.

Mice

hIL4

Strain Name：C57BL/6Smoc-Il4tm3(hIL4)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-190071

The endogenous mouse Il4 gene was completely or partially replaced by human IL4 gene via ESC targeting.

Mice

hHLA-E

Strain Name：C57BL/6Smoc-Igs2em1(hHLA-E)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-200221

The endogenous human HLA-E gene (about 11kb) was knocked into the H11 locus via CRISPR/Cas9 mediated recombination.

Mice

Sox2-CreERT2

Strain Name：C57BL/6Smoc-Sox2em1(CreERT2-polyA)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200084

The coding region of Sox2 gene was replaced by a CreERT2-polyA expression cassette.

Mice

Cx3cr1-Cre

Strain Name：C57BL/6Smoc-Cx3cr1em1(iCre)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-200079

The coding region of Cx3cr1 gene was replaced by a iCre expression cassette via CRISPR/Cas9 mediated recombination.

Mice

Sirpa-Nod

Strain Name：C57BL/6Smoc-Sirpaem1(Sirpa-Nod)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-232215

All coding sequences of C57 mouse gene exon3 were replaced with all coding sequences of Nod mouse gene exon3.

Mice

Vps54-L967Q

Strain Name：C57BL/6Smoc-Vps54em1(L967Q)/Smoc
Strain State：Developing | Cat. NO.：NM-KI-232086

These strains carry a L967Qmutation of Vps54 gene.

Mice

Mefv-hMEFV*V726A

Strain Name：C57BL/6Smoc-Mefvem1(hMEFV-V726A)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-200221

Exon 7-10 of the endogenous mouse Mefv gene was replaced by human mutation gene (exon7-10).

Mice

Avil-Cre

Strain Name：C57BL/6Smoc-Avilem1(Cre)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-215036

Cre expression cassette was knocked into the Avil gene.

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