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Models

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Mice

hCD28/hCD38(2)

Strain Name：C57BL/6Smoc-Cd28tm2(hCD28)Cd38tm2(CD38)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-210350

hCD38(NM-HU-190059) was crossed with hCD28(NM-HU-190011) to generate hCD28/hCD38 mice.

Mice

hTSLP

Strain Name：C57BL/6Smoc-Tslptm2(hTSLP)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000064
Validation Data：Presence

The endogenous mouse Tslp gene was replaced by human TSLP gene.

Mice

hCD24/hSIGLEC10

Strain Name：C57BL/6Smoc-Cd24atm1(hCD24)Siglecgtm1(hSIGLEC10)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-210367
Validation Data：Presence

hCD24(NM-HU-2000060) was crossed with hSIGLEC10(NM-HU-2000061）to generate hCD24/hSIGLEC10 mice.

Mice

hPD-L1/hCD73(2)

Strain Name：C57BL/6Smoc-Cd274tm1(hPD-L1)Nt5etm2(NT5E)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-210356

hPD-L1(NM-HU-00062) was crossed with hCD73(2)(NM-HU-200009) to generate hPD-L1/hCD73(2) mice.

Mice

hSIGLEC8(2)

Strain Name：C57BL/6Smoc-Siglecftm1(hSIGLEC8)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-210033
Validation Data：Presence

The endogenous mice Siglecf gene was replaced by human SIGLEC8 gene. While hSIGLEC8(Stock No.NM-HU-204983) mice function similarly to hSIGLEC8(2) mice,for more detailed information please contact our technical advisor.

Mice

hTNFR2/hFCGR2B

Strain Name：C57BL/6Smoc-Tnfrsf1btm2(hTNFRSF1B)Fcgr2btm3(FCGR2B)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-210404

hTNFRSF1B (NM-HU-190010) was crossed with hFCGR2B (NM-HU-2000010) to generate hTNFRSF1B/hFCGR2B mice.

Mice

hTNFRSF10B

Strain Name：C57BL/6Smoc-Tnfrsf10btm1(hTNFRSF10B)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-210005

The endogenous mice Tnfrsf10B gene was replaced by human TNFRSF10B gene

Mice

hFAS

Strain Name：C57BL/6Smoc-Fastm1(hTNFRSF6)/Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-HU-210007
Validation Data：Presence

The endogenous mice Fas gene was replaced by human FAS gene.

Mice

hIL21R

Strain Name：C57BL/6Smoc-Il21rtm1(hIL21R)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-210031
Validation Data：Presence

The endogenous mice Il21r gene was completely or partially replaced by human IL21R gene via ESC targeting.

Mice

hLILRB4

Strain Name：C57BL/6Smoc-Lilrb4atm1(hLILRB4 )Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-210024
Validation Data：Presence

The endogenous mice Lilrb4a gene was completely or partially replaced by human LILRB4 gene via CRISPR/Cas9 mediated recombination.

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