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Models

About 355 results
Mice

Fcgrt-KO

Strain Name：C57BL/6Smoc-Fcgrtem1Smoc
Strain State：Repository Live | Cat. NO.：NM-KO-00133
Validation Data：Presence  |  Publications：1piece

Fcgrt-KO mice (Stock No.NM-KO-00133）carry a knockout allele derived from the targeted deletion of exon 1-4.

Mice

hANGPTL3(4)

Strain Name：C57BL/6Smoc-Angptl3tm1(hANGPTL3)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-210036
Validation Data：Presence

The endogenous mice Angptl3 gene was replaced by human ANGPTL3 gene. While hANGPTL3(Stock No.NM-HU-200113) have been pulled from shelves for some reasons and hANGPTL3(3)(Stock No.NM-HU-210037) mice function similarly to hANGPTL3(2) mice, for more detailed information please contact our technical advisor.

Mice

h4-1BB(2)/hPD-1/hPD-L1

Strain Name：C57BL/6Smoc-Tnfrsf9tm2(TNFRSF9)Pdcd1tm1(hPDCD1)Cd274tm1(hPD-L1)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-210357

h4-1BB(2)(NM-HU-190077), hPD-L1(NM-HU-00062) and hPD-1(NM-HU-00015) was crossed together to generate h4-1BB(2)/hPD-1/hPD-L1 mice.

Mice

hB7H3/hCD28

Strain Name：C57BL/6Smoc-Cd276tm2(hCD276)Cd28tm2(hCD28)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-210353
Validation Data：Presence

hB7-H3(NM-HU-00107) was crossed with hCD28(NM-HU-190011) to generate hB7H3/hCD28 mice.

Mice

hHBB

Strain Name：C57BL/6Smoc-Hbb-bt&Hbb-bstm1(hHBB)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000080
Validation Data：Presence

The endogenous mouse Hbb-bt and Hbb-bs gene was replaced by human HBB gene.

Mice

hGLP1R

Strain Name：C57BL/6Smoc-Glp1rtm2(hGLP1R)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-200220
Validation Data：Presence  |  Publications：1piece

The endogenous mouse Glp1r gene was completely or partially replaced by human hGLP1R gene via CRISPR/Cas9 mediated recombination.

Mice

hB7H3/hPD-1

Strain Name：C57BL/6Smoc-Cd276tm2(hCD276)Pdcd1tm1(hPDCD1)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-210349

hB7-H3(NM-HU-00107) was crossed with hPD-1(NM-HU-00015) to generate hB7H3/hPD-1 mice.

Mice

hCD20(2)

Strain Name：C57BL/6Smoc-Ms4a1tm3(hCD20)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-200114
Validation Data：Presence

Extracellular and transmembrane region of the endogenous mouse Ms4a1 gene was replaced by corresponding region of human CD20 gene. While hCD20(Stock No.NM-HU-190068) mice function similarly to hCD20(2) mice,for more detailed information please contact our technical advisor.

Mice

HLA-A2.22/B2M

Strain Name：C57BL/6Smoc-H2-D1tm1(hB2M/HLA-A2)/Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-HU-210010

The endogenous mice H2-D1 gene was replaced by human B2M/HLA-A2 gene

Mice

hEPCAM

Strain Name：C57BL/6Smoc-Epcamtm1(hEPCAM)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-210032
Validation Data：Presence

The endogenous mice Epcam gene was completely or partially replaced by human EPCAM gene via ESC targeting.

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