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Models

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Mice

hCD4(BALB/c)

Strain Name:BALB/cAnSmoc-Cd4em3(hCD4)/Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-2000053

The endogenous mouse Cd4 gene was replaced by human CD4 gene.

Mice

hFCGR1A

Strain Name:C57BL/6Smoc-Fcgr1tm3(hFCGR1A)/Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-2000072

The endogenous mouse Fcgr1 gene was replaced by human FCGR1A gene.

Mice

Fcgrt-KO

Strain Name:C57BL/6Smoc-Fcgrtem1Smoc
Strain State:Repository Live | Cat. NO.:NM-KO-00133

Fcgrt-KO mice (Stock No.NM-KO-00133)carry a knockout allele derived from the targeted deletion of exon 1-4.

Mice

h4-1BB(2)/hPD-1/hPD-L1

Strain Name:C57BL/6Smoc-Tnfrsf9tm2(TNFRSF9)Pdcd1em1(hPDCD1)Cd274em1(hPD-L1)/Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-210357

h4-1BB(2)(NM-HU-190077), hPD-L1(NM-HU-00062) and hPD-1(NM-HU-00015) was crossed together to generate h4-1BB(2)/hPD-1/hPD-L1 mice.

Mice

hANGPTL3(4)

Strain Name:C57BL/6Smoc-Angptl3em1(hANGPTL3)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-210036

The endogenous mice Angptl3 gene was replaced by human ANGPTL3 gene. While hANGPTL3(Stock No.NM-HU-200113) have been pulled from shelves for some reasons and hANGPTL3(3)(Stock No.NM-HU-210037) mice function similarly to hANGPTL3(2) mice, for more detailed information please contact our technical advisor.

Mice

hB7H3/hCD28

Strain Name:C57BL/6Smoc-Cd276tm2(hCD276)Cd28em2(hCD28)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-210353

hB7-H3(NM-HU-00107) was crossed with hCD28(NM-HU-190011) to generate hB7H3/hCD28 mice.

Mice

hB7H3/hPD-1

Strain Name:C57BL/6Smoc-Cd276tm2(hCD276)Pdcd1em1(hPDCD1)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-210349

hB7-H3(NM-HU-00107) was crossed with hPD-1(NM-HU-00015) to generate hB7H3/hPD-1 mice.

Mice

hHLA-A2.22/B2M

Strain Name:C57BL/6Smoc-H2-D1em1(hB2M/HLA-A2)/Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-HU-210010

The endogenous mice H2-D1 gene was replaced by human B2M/HLA-A2 gene

Mice

hGLP1R

Strain Name:C57BL/6Smoc-Glp1rem2(hGLP1R)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-200220

The endogenous mouse Glp1r gene was completely or partially replaced by human hGLP1R gene via CRISPR/Cas9 mediated recombination.

Mice

hCD24/hSIGLEC10

Strain Name:C57BL/6Smoc-Cd24atm1(hCD24)Siglecgtm1(hSIGLEC10)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-210367

hCD24(NM-HU-2000060) was crossed with hSIGLEC10(NM-HU-2000061)to generate hCD24/hSIGLEC10 mice.

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