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Models

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Mice

Fcgr2b-Fcgr3-Fcgr4-KO/hCTLA-4

Strain Name:C57BL/6Smoc-Fcgr2bem1Fcgr3em1Fcgr4em1Ctla4em1(hCTLA4)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KO-220069

The Fcgr2b-Fcgr3-Fcgr4-KO/hCTLA4 mouse model was obtained by deleting all sequences from upstream of Fcgr3 gene to the 3'UTR of Fcgr2b gene in the hCTLA4(NM-HU-00014) mouse.

Mice

hIL2

Strain Name:C57BL/6Smoc-Il2tm3(hIL2)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-190048

The endogenous mouse Il2 gene was replaced by human IL2 gene.

Mice

Fcgr2b-Fcgr3-Fcgr4-KO/hPD-1

Strain Name:C57BL/6Smoc-Fcgr2bem1Fcgr3em1Fcgr4em1Pdcd1em1(hPDCD1)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KO-220068

The Fcgr2b-Fcgr3-Fcgr4-KO/hPD-1 mouse model was obtained by deleting all sequences from upstream of Fcgr3 gene to the 3'UTR of Fcgr2b gene in the hPD-1(NM-HU-00015) mouse.

Mice

hOX40L(2)

Strain Name:C57BL/6Smoc-Tnfsf4em2(TNFSF4)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-200005

The endogenous mouse Tnfsf4 gene was replaced by human TNFSF4 gene . While hOX40L(Stock No.NM-HU-00070) mice function similarly to hOX40L(2) mice,for more detailed information please contact our technical advisor.

Mice

hPD-1/hVEGFR2

Strain Name:C57BL/6Smoc-Pdcd1em1(hPDCD1)Kdrtm2(hKDR)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-2000098

hPD-1(NM-HU-00015) was crossed with hKDR(NM-HU-00098) to generate hPD-1/hKDR.

Mice

hIL3/hCSF2

Strain Name:C57BL/6Smoc-Il3tm3(hIL3)Csf2tm3(hCSF2)/Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-190065

The endogenous mouse Il3 and Csf2 gene was replaced by human IL3 and CSF2 gene.

Mice

hCTLA-4(2)

Strain Name:C57BL/6Smoc-Ctla4em2(hCTLA4)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-190038

Extracellular domain of mouse Ctla4 gene was replaced by human CTLA4 gene. While hCTLA4(Stock No.NM-HU-00014) mice function similarly to hCTLA4(2) mice,for more detailed information please contact our technical advisor.

Mice

hIL5/hIL5R(2)

Strain Name:C57BL/6Smoc-Il5tm3(hIL5)Il5raem2(hIL5RA)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-HU-220010

The endogenous mouse Il5 and Il5ra genes was replaced by human IL5 and IL5ra genes. While hIL5/hIL5R(Stock No.NM-HU-2000101) mice and hIL5/hIL5R(3)(Stock No.NM-HU-220011) function similarly to hIL5/hIL5R(2) mice, for more detailed information please contact our technical advisor.

Mice

hIL5/hIL5R(3)

Strain Name:C57BL/6Smoc-Il5tm3(hIL5)Il5raem3(hIL5RA)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-220011

The endogenous mouse Il5 and Il5ra genes was replaced by human IL5 and IL5ra genes. While hIL5/hIL5R(Stock No.NM-HU-2000101) mice and hIL5/hIL5R(2)(Stock No.NM-HU-220010) function similarly to hIL5/hIL5R(3) mice, for more detailed information please contact our technical advisor.

Mice

hIL17RA

Strain Name:C57BL/6Smoc-Il17ratm1(hIL17RA)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-190049

The endogenous mouse Il17ra gene was replaced by human IL17RA gene.

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