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Models

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Mice

hIL18

Strain Name:C57BL/6Smoc-Il18tm1(hIL18)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-210038

The endogenous mice Il18 gene was replaced by human IL18 gene.

Mice

hIL7R

Strain Name:C57BL/6Smoc-Il7rtm1(hIL7R)Smoc
Strain State:Developing | Cat. NO.:NM-HU-210027

The endogenous mice Il7r gene was completely or partially replaced by human IL7R gene via ESC targeting.

Mice

hPSGL-1(2)

Strain Name:C57BL/6Smoc-Selplgem2(hSELPLG)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-210026

The endogenous mice Selplg gene was completely or partially replaced by human SELPLG gene via CRISPR/Cas9 mediated recombination.

Mice

hIL18BP

Strain Name:C57BL/6Smoc-Il18bpem1(hIL18BP)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-210039

The endogenous mice Il18bp gene was replaced by human IL18BP gene.

Mice

hSIRPA(2)/hCD47/hCTLA-4

Strain Name:C57BL/6Smoc-Sirpatm2(hSIRPA)Cd47em1(hCD47)Ctla4em1(hCTLA4) Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-210368

hCTLA4(NM-HU-00014) was crossed with hSIRPA(2)/hCD47(NM-HU-2000111)to generate hSIRPA(2)/hCD47/hCTLA4 mice

Mice

hLILRB4

Strain Name:C57BL/6Smoc-Lilrb4aem1(hLILRB4 )Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-210024

The endogenous mice Lilrb4a gene was completely or partially replaced by human LILRB4 gene via CRISPR/Cas9 mediated recombination.

Mice

hFOXP2

Strain Name:C57BL/6Smoc-Foxp2em1(hFOXP2)/Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-210002

The endogenous mice Foxp2 gene was replaced by human FOXP2 gene

Mice

hSIRPA(2)/hCD47/hPD-1/hPD-L1

Strain Name:C57BL/6Smoc-Sirpatm2(hSIRPA)Cd47em1(hCD47)Pdcd1em1(hPDCD1)Cd274em1(hPD-L1)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-210358

hSIRPA(2)(NM-HU-18015),hCD47(NM-HU-00050), hPD-1(NM-HU-00015), hPD-L1(NM-HU-00062)was crossed together to generate hSIRPA(2)/hCD47/hPD-1/hPD-L1 mice.

Mice

hHLA-E

Strain Name:C57BL/6Smoc-Igs2em1(hHLA-E)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-200221

The endogenous human HLA-E gene (about 11kb) was knocked into the H11 locus via CRISPR/Cas9 mediated recombination.

Mice

hHLA-DPA1*03: 01

Strain Name:C57BL/6Smoc-H2-Aaem1(hHLA-DPA1*03: 01)/Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-210009

The endogenous mice H2-Aa gene was replaced by human HLA-DPA1*03: 01 gene

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