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Mice

Drd1-2A-CreERT2

Strain Name：C57BL/6Smoc-Drd1em1(2A-CreERT2-WPRE-pA)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-18016

A 2A-CreERT2-WPRE-pA coexpression cassette is inserted befor the stop codon of mouse Drd1 gene via homologous recombination to establish a tamoxifen inducible Drd1-CreERT2 tool stain. This strain can be used to knockout target gene in Drd1+ cells after tamoxifen treatment when crossed with mice which carry loxp sites flanking target gene.

Mice

Ly6g-2A-CreERT2

Strain Name：C57BL/6Smoc-Ly6gem3(2A-CreERT2)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200218

A 2A-CreERT2 expression cassette was knocked into the Ly6g gene start codon site.

Mice

Lyz2-2A-CreERT2

Strain Name：C57BL/6Smoc-Lyz2em1(2A-CreERT2-WPRE-pA)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-18018

A 2A-CreERT2-WPRE-pA coexpression cassette is inserted befor the stop codon of mouse Lyz2 gene via homologous recombination to establish a tamoxifen inducible Lyz2-CreERT2 tool stain. This strain can be used to knockout target gene in Lyz2+ cells after tamoxifen treatment when crossed with mice which carry loxp sites flanking target gene.

Mice

Slco1c1-2A-CreERT2

Strain Name：C57BL/6Smoc-Slco1c1em1(2A-CreERT2)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200262

2A-CreERT2 expression cassette was knocked into the Slco1c1 gene stop codon site. Slco1c1 encodes a member of the organic anion transporter family. The encoded protein is a transmembrane receptor that mediates the sodium-independent uptake of thyroid hormones in brain tissues. This protein has particularly high affinity for the thyroid hormones thyroxine, tri-iodothyronine and reverse tri-iodothyronine. When Slco1c1-2A-CreERT2 mice are bred with mice containing loxP-flanked sequence, tamoxifen-inducible, Cre-mediated recombination will result in deletion of the floxed sequences in SLCO1C1 positive cells.

Mice

Bmi1-IRES-CreERT2

Strain Name：C57BL/6Smoc-Bmi1em1(IRES-CreERT2)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-200095

A IRES-CreERT2 expression cassette was knocked into the Bmi1 gene stop codon site.

Mice

Cd68-IRES-CreERT2

Strain Name：C57BL/6Smoc-Cd68em1(IRES-CreERT2)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-200162

A IRES-CreERT2 expression cassette was knocked into the Cd68 gene stop codon site.

Mice

Il17a-2A-CreERT2

Strain Name：C57BL/6Smoc-Il17aem1(2A-CreERT2)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-00059

A 2A-Cre cassette was inserted before stop codon of mouse Il17a gene which is known as a T cell marker.

Mice

Ctsk-2A-CreERT2

Strain Name：C57BL/6Smoc-Ctskem1(2A-CreERT2-WPRE-polyA)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-200067

A 2A-CreERT2-WPRE-polyA expression cassette was knocked into the Ctsk gene stop codon site.

Mice

Nkx2-1-CreERT2

Strain Name：C57BL/6Smoc-Nkx2-1em1(CreERT2-pA)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200123

A CreERT2-pA expression cassette was knocked into the Nkx2-1 gene start codon site. Nkx2-1, a key molecule in lung development, is expressed in adult bronchial and alveolar type Ⅱ epithelial cells. Besides, Nkx2-1 expression as a prognostic marker is also been applied to lung cancer research including lung adenocarcinoma.

Mice

Krt5-2A-CreERT2

Strain Name：C57BL/6Smoc-Krt5em1(2A-CreERT2)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-190016

The 2A-CreERT2 cassette is inserted before 3'UTR region of Krt5 gene.

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