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R26-CAG-EGFP(2)

Strain Name：C57BL/6Smoc-Gt(ROSA)26Sor^{em1(CAG-EGFP-WPRE-polyA)Smoc}
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-190089

These mice harbor a CAG-EGFP-WPRE-polyA cassette in the Rosa26 locus.1 generated by homologous recombination. While R26-CAG-EGFP(Stock No.NM-KI-190088) and R26-CAG-EGFP(3)(Stock No.NM-KI-190090) function similarly to R26-CAG-EGFP(2) mice,for more detailed information please contact our technical advisor.

R26-CAG-EGFP(3)

Strain Name：C57BL/6Smoc-Gt(ROSA)26Sor^{em2(CAG-EGFP-WPRE-polyA)Smoc}
Strain State：Repository Live | Cat. NO.：NM-KI-190090

These mice harbor a CAG-EGFP-WPRE-polyA cassette in the Rosa26 locus.2 generated by homologous recombination. While R26-CAG-EGFP(Stock No.NM-KI-190088) and R26-CAG-EGFP(2)(Stock No.NM-KI-190089) function similarly to R26-CAG-EGFP(3) mice,for more detailed information please contact our technical advisor.

Ncoa3-KO

Strain Name：C57BL/6Smoc-Ncoa3^tm2Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-210343

Ncoa3-KO mice (Stock No.NM-KO-210343） carry a knockout allele derived from the targeted deletion of exon 3-14. While Ncoa3-KO(2) mice (Stock No.NM-KO-2114118）carrying the exon 6 deletion. This strain originates from a customer donation. Purchase requires permission from the owner of the mouse proprietary rights. Contact: Baylor College of Medicine, Xu Jianming, jxu@bcm.tmc.edu.

These Mice Are About to Go Viral Because of the Nobel Prize!

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The 2024 Nobel Prize in Physiology or Medicine awarded to Victor Ambros and Gary Ruvkun for their discovery of microRNA (miRNA) highlights its revolutionary role in gene regulation and disease treatment. This article explores miRNA's impact on neuroscience, cancer, and cardiovascular research. GenoBioTX offers advanced microRNA mouse models and customized genetic solutions, empowering researchers with essential tools to drive innovation in miRNA studies and therapeutic developments.

Enhancing Your Research: How GenoBioTX's Gene Editing Technology Empowers Research Breakthroughs

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This seminar will introduce GenoBioTX’s gene editing platform and technology, highlighting how these techniques can enhance your research projects. We will cover the history of genome editing, provide an overview of GenoBioTX’s gene editing platform and technology, and present case studies that demonstrate how our gene editing techniques can facilitate research advancements.

Customizing Mouse Models: Delivering in 100 Days to Speed Up Your Research!

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At GenoBioTX, we understand that the lengthy wait times for gene-modified mouse models can hinder your research progress. Traditional methods often require 6-9 months, leading to delays and increased costs. That’s why we’re thrilled to introduce our innovative service designed to streamline this process and deliver results faster.

Webinar on Advances in Antibody-Drug Conjugates (ADCs) Development & Preclinical Models

Antibody-Drug Conjugates ADC Development Preclinical Models Targeted Cancer Therapies GenoBioTX ADC Webinar Biopharma Research Oncology Biochemistry Cancer Treatment Preclinical Evaluation Monoclonal Antibodies Small Molecule Drugs

Join us for a webinar on June 26th, 2024, exploring the development and preclinical evaluation of Antibody-Drug Conjugates (ADCs). Learn from Dr. Hua Wei, VP of the Industrial Clients Department at GenoBioTX, about ADC components, mechanisms, historical evolution, and future directions.

Advancing Cancer Therapy: Harnessing In Vivo Tumor Models for Breakthrough Drug Development

Cancer therapy advancements In vivo tumor models Preclinical cancer research Drug development in oncology Gene-modified cell lines Immuno-oncology Tumor modeling for drug discovery Cancer drug development Animal modeling services Cancer drug preclinical models

Join us for an insightful webinar exploring the critical role of in vivo tumor models in advancing cancer drug therapy. We will provide an overview of the diverse tumor models developed by our company, highlighting case studies demonstrating their effectiveness in preclinical cancer research. The session will delve into the comprehensive use of gene-modified cell lines and genetically modified spontaneous mouse models, showcasing their application in mimicking human cancer biology. We will conclude with a brief introduction to our company and our commitment to accelerating cancer drug development through innovative animal modeling services.

New Service Launch: Mouse Bone Metastasis Cancer Model and Pain-Related Behavior Assessment!

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We are excited to announce that GenoBioTX has launched a new service featuring mouse bone metastasis cancer models and pain-related behavior assessment, designed to support cancer research and pain management effectively.

Harnessing the Power of the Cre-loxP System: Benefits, Challenges, and Applications

This webinar will introduce the Cre-loxP system, a powerful genetic tool that has revolutionized biological research by allowing for conditional gene knockout, knockdown, and overexpression. We will cover the history of the genetic recombination systems, discuss how they enable precise control of gene expression in specific cell types or at specific developmental stages, and present GenoBioTX’s genetically modified models utilizing this method.