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Models

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Mice

Per1-KO

Strain Name:C57BL/6Smoc-Per1em1Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KO-191063

Exon 7 of Per1 gene was deleted to generate Per1 knockout mice.

Mice

Bhlhe40-KO

Strain Name:C57BL/6Smoc-Bhlhe40em1Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KO-191085

Exon 2 of Bhlhe40 gene was deleted to generate Bhlhe40 knockout mice. While Bhlhe40-KO(2) mice (Stock No.NM-KO-210446)carrying the Exon 1-4 deletion.

Mice

Dyrk1a-Flox

Strain Name:C57BL/6Smoc-Dyrk1atm1(flox)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-CKO-200167

These mice carry loxP sites flanking exon 5-6 of Dyrk1a gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Dyrk1a gene.

Mice

Plcb4-KO

Strain Name:C57BL/6Smoc-Plcb4em1Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KO-191012

Exon 7 of Plcb4 gene was deleted to generate Plcb4 knockout mice.

Mice

Bmal1-Flox

Strain Name:C57BL/6Smoc-Bmal1em1(flox)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-CKO-200063

These mice carry loxP sites flanking exon 8 of Bmal1 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Bmal1 gene.

Mice

Hrh1-KO

Strain Name:C57BL/6Smoc-Hrh1em1Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KO-190599

Exon 3 of Hrh1 gene was deleted to generate Hrh1 knockout mice.

Mice

Cpt1a-Flox

Strain Name:B6;129S-Cpt1atm1(flox)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-CKO-00056

These mice carry loxP sites on either side of exon 3. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of the gene.

Literature

Necdin regulates BMAL1 stability and circadian clock through SGT1-HSP90 chaperone machinery

Model Organisms:Mouse Product & Service:Ndn Research field:Circadian clocks

Pages

Metabolic Analysis

Metabolic analysis

There are many mice models used to mimic human metabolic diseases, such as diabetes and obesity, which are caused by nutritional imbalances and metabolic disorders. The detection and analysis of sugar and lipid metabolism phenotypes in these model mice are crucial for the establishment of model mice, the study of disease progression, and the research on the pathogenesis. Shanghai Model Organisms can help your research on metabolism by providing you with a series of testing tools for glucose and lipid metabolisms.

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