Welcome to Advanced Search

Models

About 524 results
Mice

Slc6a11-CreERT2

Strain Name：C57BL/6Smoc-Slc6a11em1(CreERT2-polyA(SV40)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-200130
Validation Data：Presence

A CreERT2-polyA expression cassette was knocked into the Slc6a11 gene start codon site. Slc6a11 encodes GAT3 (Gabt4), a sodium-dependent transporter that uptakes the inhibitory neurotransmitter gamma-aminobutyric acid (GABA), which ends the GABA neurotransmission. When Slc6a11-CreERT2 mice are bred with mice containing loxP-flanked sequence, tamoxifen-inducible, Cre-mediated recombination will result in deletion of the floxed sequences in SLC6A11positive cells. Defects in Slc6a11 may result in epilepsy or behavioral and intellectual defects.

Mice

Ntrk2-CreERT2

Strain Name：C57BL/6Smoc-Ntrk2em1(CreERT2-WPRE-polyA)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-200146
Validation Data：Presence

A CreERT2-WPRE-polyA expression cassette was knocked into the Ntrk2 gene start codon site. Ntrk2 encodes the tropomyosin receptor kinase B (TrkB), transmission through which neurotrophic factors modify differentiation, plasticity, and synaptic transmission. When these Ntrk2-CreERT2 mice are bred with mice containing a loxP-flanked sequence of interest, tamoxifen-inducible, Cre-mediated recombination will result in deletion of the flanked sequences in Ntrk2 expressing cells.

Mice

Slco1c1-2A-CreERT2

Strain Name：C57BL/6Smoc-Slco1c1em1(2A-CreERT2)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200262
Validation Data：Presence

2A-CreERT2 expression cassette was knocked into the Slco1c1 gene stop codon site. Slco1c1 encodes a member of the organic anion transporter family. The encoded protein is a transmembrane receptor that mediates the sodium-independent uptake of thyroid hormones in brain tissues. This protein has particularly high affinity for the thyroid hormones thyroxine, tri-iodothyronine and reverse tri-iodothyronine. When Slco1c1-2A-CreERT2 mice are bred with mice containing loxP-flanked sequence, tamoxifen-inducible, Cre-mediated recombination will result in deletion of the floxed sequences in SLCO1C1 positive cells.

Mice

Bhlha15-CreERT2

Strain Name：C57BL/6Smoc-Bhlha15em1(CreERT2)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-200080
Validation Data：Presence

The coding region of Bhlha15 gene was replaced by a CreERT2 expression cassette.Besides,a kozak-CreERT2-WPRE-polyA expression cassette were knock into the Bhlha15 gene start codon site to generate Bhlha15-CreERT2(2)(Stock No. NM-KI-200158) mice. Bhlha15(basic helix-loop-helix family member a15) is also known as Mist1. The gene product is involved in controlling exocrine secretion from the pancreas, small intestine and stomach. When crossed with a strain carrying a gene flanked by loxP sites, the flanked gene will be removed in cells expressing Bhlha15.

Mice

Ms4a2-KO

Strain Name：C57BL/6Smoc-Ms4a2em1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-190839

Exon 2 of Ms4a2 gene was deleted to generate Ms4a2 knockout mice.

Mice

Abi3bp-Flox

Strain Name：B6;129S-Abi3bptm1(flox)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-CKO-00009

An frt-neo-frt cassette was inserted before exon 4. And these mice possess loxP sites on either side of exon 4. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of the gene.

Mice

Tafa5-KO

Strain Name：C57BL/6Smoc-Tafa5em1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-200706

Exon 2 of Tafa5 gene was deleted to generate Tafa5 knockout mice.

Mice

Lyz2-CreERT2-IRES-EGFP

Strain Name：C57BL/6Smoc-Lyz2em2(CreERT2-IRES-EGFP)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-18047
Validation Data：Presence

A Kozak-CreERT2-IRES-EGFP expression cassette was knocked into the Lyz2 gene start codon site by homologous recombination.

Mice

Foxp1-Flox

Strain Name：C57BL/6Smoc-Foxp1tm1(flox)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-CKO-200168

These mice carry loxP sites flanking exon 6-7 of Foxp1 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Foxp1 gene.

Mice

Il24-KO

Strain Name：C57BL/6Smoc-Il24em1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-190494

Exon 2-4 of Il24 gene was deleted to generate Il24 knockout mice.

Email Back to top