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Models

About 1,095 results
Mice

huHSC-(NMG)

Strain Name：huHSC-(NMG)
Strain State：Repository Live | Cat. NO.：NM-NSG-017

After irradiation, NMG mice are injected with CD34+ hematopoietic stem cells (CD34+ HSC).

Mice

huPBMC-(NMG)

Strain Name：huPBMC-(NMG)
Strain State：Repository Live | Cat. NO.：NM-NSG-015

NMG mice are injected with human peripheral blood mononuclear cells (huPBMCs).

Mice

Prcp-KO

Strain Name：C57BL/6Smoc-Prcpem1Smoc
Strain State：Developing | Cat. NO.：NM-KO-200424

Exon 3-4 of Prcp gene was deleted to generate Prcp knockout mice.

Mice

Pax7-IRES-Cre

Strain Name：C57BL/6Smoc-Pax7em1(IRES-iCre)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-200120

A IRES-iCre expression cassette was knocked into the Pax7 gene stop codon site. Pax7 is expressed in myogenic progenitor cells. Pax7 is essential for the myogenic potential, survival, and proliferation of myogenic progenitors. When crossed with a strain carrying a gene flanked by loxP sites, the flanked gene will be removed in cells expressing Pax7.

Mice

Pax7-IRES-CreERT2

Strain Name：C57BL/6Smoc-Pax7em1(IRES-Cre-ERT2)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200099

A IRES-Cre-ERT2 expression cassette was knocked into the Pax7 gene stop codon site. Pax7 is expressed in myogenic progenitor cells. Pax7 is essential for the myogenic potential, survival, and proliferation of myogenic progenitors. When crossed with a strain carrying a gene flanked by loxP sites, the flanked gene will be removed in cells expressing Pax7 after tamoxifen treatment.

Mice

Foxl1-2A-CreERT2

Strain Name：C57BL/6Smoc-Foxl1em1(2A-CreERT2)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-00135

A 2A-CreERT2 coexpression cassette is inserted before the stop codon of mouse Foxl1 gene via homologous recombination to establish a Foxl1-CreERT2 recombinase tool stain. This strain can be used to knockout target gene inFoxl1+ cells after tamoxifen treatment when crossed with flox mice.

Mice

Sox9-IRES-Flp

Strain Name：B6;129S-Sox9tm1(IRES-Flp)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-00131

An IRES-Flp-polyA coexpression cassette is inserted at 3' terminal of mouse Sox9 gene via homologous recombination to establish a Sox9-Flp recombinase tool stain. This strain can be used to knockout target gene in Sox9+ cells when crossed with mice which carry frt sites flanking target gene.

Mice

Tie1-2A-Cre

Strain Name：C57BL/6Smoc-Tie1em1(2A-Cre)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-18023

A 2A-Cre coexpression cassette is inserted befor the stop codon of mouse Tie1 gene via homologous recombination to establish a tamoxifen inducible Tie1-Cre tool stain. This strain can be used to knockout target gene in Tie1+ cells when crossed with mice which carry loxp sites flanking target gene.

Mice

Prl-IRES-CreERT2

Strain Name：C57BL/6Smoc-Prlem1(IRES-CreERT2)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-200170

A IRES-CreERT2 expression cassette was knocked into the Prl gene stop codon site. Prolactin (PRL) is a hormone synthesized and secreted by lactotroph cells in the anterior pituitary gland. PRL is responsible for lactogenesis and other processes associated with it. When crossed with a strain carrying a gene flanked by loxP sites, the flanked gene will be removed in cells expressing cre.

Mice

Aplnr-2A-DreERT2

Strain Name：C57BL/6Smoc-Aplnrem1(2A-DreERT2)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-00132

A 2A-DreERT2-SV40polyA coexpression cassette is inserted befor the stop codon of mouse Aplnr gene via homologous recombination to establish a tamoxifen inducible Aplnr-DreERT2 tool stain. This strain can be used to knockout target gene in Aplnr+ cells after tamoxifen treatment when crossed with mice which carry rox sites flanking target gene.

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