Strain Name:C57BL/6Smoc-Ighmem1Ighdem1Smoc
Strain State:Repository Live | Cat. NO.:NM-KO-200610
Exon 1-6 of Ighm and exon 1-5 of Ighd gene was deleted to generate Ighm and Ighd knockout mice. Homozygous mutant mice lack mature B cells. It may be useful as a model for B cell immunodeficiency found in humans.