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Models

About 26 results
Mice

Adgra2-Flox

Strain Name：B6;129S-Adgra2tm1(flox)Smoc
Strain State：Repository Live | Cat. NO.：NM-CKO-00101

These Gpr124 flox mutant mice possess loxP sites flanking exon 2 of the G protein-coupled receptor 124 (Gpr124) targeted gene. Homozygotes are viable, fertile, normal in size and do not display any gross physical or behavioral abnormalities.

Mice

Slc6a11-CreERT2

Strain Name：C57BL/6Smoc-Slc6a11em1(CreERT2-polyA(SV40)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-200130

A CreERT2-polyA expression cassette was knocked into the Slc6a11 gene start codon site. Slc6a11 encodes GAT3 (Gabt4), a sodium-dependent transporter that uptakes the inhibitory neurotransmitter gamma-aminobutyric acid (GABA), which ends the GABA neurotransmission. When Slc6a11-CreERT2 mice are bred with mice containing loxP-flanked sequence, tamoxifen-inducible, Cre-mediated recombination will result in deletion of the floxed sequences in SLC6A11positive cells. Defects in Slc6a11 may result in epilepsy or behavioral and intellectual defects.

Mice

C57BL/6

Strain Name：C57BL/6Smoc
Strain State：Repository Live | Cat. NO.：SM-001

C57BL/6 mice have a high reproductive capacity, a long life span, and a low tumor susceptibility. Male mice are aggressive and fight frequently. Diet can cause obesity, type II diabetes, and atherosclerosis in these mice. The C57BL/6 mouse is the first to have its entire genome sequenced. It is the most extensively used inbred mouse strain as a genetic basis for congenic and mutant mice. It is also used in genetics, metabolism, immunology, neurology, behavioral research, pharmacodynamics, and medication safety evaluation.

Mice

Prkce-KO

Strain Name：C57BL/6Smoc-Prkceem1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-190861

Exon 2 of Prkce gene was deleted to generate Prkce knockout mice.

Mice

Bmal1-Flox

Strain Name：C57BL/6Smoc-Bmal1em1(flox)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-CKO-200063

These mice carry loxP sites flanking exon 8 of Bmal1 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Bmal1 gene.

Mice

Per1-KO

Strain Name：C57BL/6Smoc-Per1em1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-191063

Exon 7 of Per1 gene was deleted to generate Per1 knockout mice.

Mice

Dgcr2/Hira-KO

Strain Name：C57BL/6Smoc-Dgcr2em1Hiraem1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-18060

the sgRNAs were designed targeting Dgcr2 intron9 and Hira intron24 resulting in a sequence deletion of approximately 0.11 mb between the Dgcr2 gene and the Hira gene.

Mice

Adra1d-KO

Strain Name：C57BL/6Smoc-Adra1Dem1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-190908

Exon 2 of Adra1d gene was deleted to generate Adra1d knockout mice.

Mice

Cnr1-KO

Strain Name：C57BL/6Smoc-Cnr1em1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-190945

Exon 2 of Cnr1 gene was deleted to generate Cnr1 knockout mice.

Mice

Hcrtr2-KO

Strain Name：C57BL/6Smoc-Hcrtr2em1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-190610

Exon 2 of Hcrtr2 gene was deleted to generate Hcrtr2 knockout mice.

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