Welcome to Advanced Search

Models

About 185 results
Mice

NMG

Strain Name：NOD.Cg-PrkdcscidIl2rgem1Smoc
Strain State：Repository Live | Cat. NO.：NM-NSG-001

Prkdc and Il2rg genes were both knocked-out in NOD mice.  Lacking mature T, B and NK cells Low immune rejection against human cells and tissues Good tumorigenicity so that a small number of cells can form tumors. Significant improvement in the survival of transplanted human cells and tissues Suitable for the transplantation of human hematopoietic stem cells and the preparation of humanized mouse models Suitable as the carrier mice for the transplantation of heterologous cells and tissues

Mice

NOD SCID

Strain Name：NOD.Cg-Prkdcscid/NifdcSmoc
Strain State：Repository Live | Cat. NO.：SM-019

The scid mutation has been transferred onto a diabetes-susceptible Non-Obese Diabetic (NOD) background. NOD-Scid mice do not develop diabetes, lack T and B cells, and are inherently immune deficient, making them good recipients for transplantation of human hematopoietic stem cells and human solid tumors. 

Mice

Atp4b-IRES-CreERT2(2)

Strain Name：C57BL/6Smoc-Atp4bem2(IRES-CreERT2)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-210119

An IRES-CreERT2 expression cassette was knocked into the Atp4b gene stop codon site. Besides,An IRES-CreERT2-WPRE-pA expression cassette were knock into the Atp4b gene start codon site to generate Atp4b-IRES-CreERT2(Stock No. NM-KI-210118) mice. ATP4B could serve as a tumor suppressor in the tumorigenesis and progression. This strain is useful in studying the function of gastric parietal cells in gastric epithelial homeostasis. When crossed with a strain carrying a gene flanked by loxP sites, the flanked gene will be removed in cre-expressing cells after tamoxifen treatment.

Mice

Tnfrsf1a/Tnfrsf1b-KO

Strain Name：C57BL/6Smoc-Tnfrsf1aem1Smoc Tnfrsf1aem1Smoc
Strain State：Repository Live | Cat. NO.：NM-KO-18036

This strain is also called p55/p75-KO. The Tnfrsf1a and Tnfrsf1b double knockout mouse models were obtained by knocking out both exon 2-5 region of mouse Tnfrsf1a gene and exon2 of mouse Tnfrsf1b gene. Tnfrsf1a and Tnfrsf1b deletion (p55 and p75 deficiency) homozygous mice are viable and fertile, and these homozygous mice fail to bind TNF (tumor necrosis factor).

Mice

Eif4ebp1-KO

Strain Name：C57BL/6Smoc-Eif4Ebp1em1Smoc
Strain State：Repository Live | Cat. NO.：NM-KO-191088

Exon 1 and exon 2 of Eif4ebp1 gene was deleted to generate Eif4ebp1 knockout mice.

Mice

Cav1-KO

Strain Name：C57BL/6Smoc-Cav1em1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-190930

Exon 3 of Cav1 gene was deleted to generate Cav1 knockout mice.

Mice

Tmem123-KO

Strain Name：C57BL/6Smoc-Tmem123em1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-191154

Exon 3 of Tmem123 gene was deleted to generate Tmem123 knockout mice.

Mice

Eif4e-KO

Strain Name：C57BL/6Smoc-Eif4Eem1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-191115

Exon 4-5 of Eif4e gene was deleted to generate Eif4e knockout mice.

Mice

Ppp2cb-KO

Strain Name：C57BL/6Smoc-Ppp2Cbem1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-191016

Exon 4-6 of Ppp2cb gene was deleted to generate Ppp2cb knockout mice.

Mice

Rassf4-KO

Strain Name：C57BL/6Smoc-Rassf4em1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-191025

Exon 3 of Rassf4 gene was deleted to generate Rassf4 knockout mice.

Email Back to top