Welcome to Advanced Search

Models

About 181 results
Mice

Cdh8-KO

Strain Name：C57BL/6Smoc-Cdh8em1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-190934

Exon 6 of Cdh8 gene was deleted to generate Cdh8 knockout mice.

Mice

Csf1-KO

Strain Name：C57BL/6Smoc-Csf1em1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-190063

This Csf1 knockout mouse model was generated by knocking out the exon 4-5 region of the Csf1 .

Mice

Il34-KO

Strain Name：C57BL/6Smoc-Il34em2Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-190501

Exon 3 of Il34 gene was deleted to generate Il34 knockout mice.

Mice

Ranbp2-Flox

Strain Name：C57BL/6Smoc-Ranbp2tm1(flox)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-CKO-200030

These mice carry loxP sites flanking exon 3 of Ranbp2 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Ranbp2 gene.

Mice

Ninj1-KO

Strain Name：C57BL/6Smoc-Ninj1em2Smoc
Strain State：Repository Live | Cat. NO.：NM-KO-200615

Exon 2 of Ninj1 gene was deleted to generate Ninj1 knockout mice.

Mice

Sec31a-KO

Strain Name：C57BL/6Smoc-Sec31aem1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-200470

Exon 3 of Sec31a gene was deleted to generate Sec31a knockout mice.

Mice

Ctnnb1-Flox

Strain Name：C57BL/6Smoc-Ctnnb1em1(flox)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-CKO-200154

These mice carry loxP sites flanking exon 2-6 of Ctnnb1 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Ctnnb1 gene.

Mice

Dicer1-Flox

Strain Name：C57BL/6Smoc-Dicer1em1(flox)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-CKO-200158

These mice carry loxP sites flanking exon 23 of Dicer1 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Dicer1 gene.

Mice

H11-CAG-LSL-Myc

Strain Name：C57BL/6Smoc-Igs2em1(CAG-LSL-Myc)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-00039

The c-Myc gene (also known as Myc) is abnormally expressed in many tumors and plays a critical role in the regulation of cell proliferation, growth and metabolism, gene instability, stimulation of angiogenesis, malignant transformation, cell differentiation and apoptosis. These mice harbor a loxP-flanked STOP cassette preventing transcription of a CAG promoter-driven Myc oncogene. The targeted mutation was inserted into the Hipp11(H11) locus by homologous recombination. Myc is expressed when bred to mice that express Cre recombinase.

Mice

Rag1-KO(Rag1-EGFP)

Strain Name：B6;129S-Rag1tm1(loxP-EGFP-PolyA-loxP-Neo-loxP)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-00069

A loxP-EGFP-PolyA-loxP-Neo-loxP expression cassette was knocked into the Rag1 gene start codon site. As a Rag1 knockout mouse model, this stain can be used in subcutaneous inoculation of liver cancer tissues and tumor cells. Tumors can esaily form and grow. The amount of T and B lymphocytes in peripheral blood of mice was extremely low tested by FACS, which was comparable to or lower than that of Nude mice, and there was a significant difference compared with wild type mice. The pathological sections of HE staining of tumor tissues showed that the tumor sections of Rag1 KO mice and Nude mice were similar. This strain has the potential to replace Nude, NOD-SCID mice as a tumor-bearing mouse model.

Email Back to top