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Models

About 181 results
Mice

R26-LSL-hEZH2-IRES-Luc-2A-tdTomato

Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-LSL-EZH2-IRES-luciferase-2A-tdTomato)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-18053

A SA-2xpolyA-CAG-Loxp-Stop-Loxp-human EZH2 cDNA-IRES-luciferase-2A-tdTomato-wpre-polyA cassette was knocked into the mouse Rosa26 locus . This strain of mice can be mated with mice expressing Cre recombinase so that human EZH2 could be expressed after exposure to Cre recombinase.

Mice

R26-CAG-LSL-hNRF2-IRES-Luc-2A-tdTomato

Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-LSL-NRF2-IRES-luciferase-2A-tdTomato)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-18050

A SA-2xpolyA-CAG-LSL-human NRF2-IRES-luciferase-2A-tdTomato-wpre-polyA cassette was knocked into the mouse Rosa26 locus . This strain of mice can be mated with mice expressing Cre recombinase to express human NRF2 and a reporter gene in certain cells or tissues that expressing Cre recombinase.

Mice

KPC(2)

Strain Name：C57BL/6Smoc-Trp53tm7(R270H-flox)Krasem4(LSL-G12D)Tg(Pdx1-cre)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-220014

Trp53-LSL-R270H, Kras-LSL-G12D were crossed with Pdx1-Cre-Tg to generate KPC mice. While KPC mice function similarly to KPC(2) mice, for more detailed information please contact our technical advisor.

Mice

hHER2

Strain Name：C57BL/6Smoc-Erbb2tm1(hERBB2)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-200115

The endogenous mouse Erbb2 gene was replaced by human ERBB2 gene.

Mice

Pidd1-KO

Strain Name：C57BL/6Smoc-Pidd1em1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-191165

Exon 3-6 of Pidd1 gene was deleted to generate Pidd1 knockout mice.

Mice

Cdh6-KO

Strain Name：C57BL/6Smoc-Cdh6em1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-200111

Exon 3 of Cdh6 gene was deleted to generate Cdh6 knockout mice.

Mice

Cdkn2a-KO(p19-KO)

Strain Name：C57BL/6Smoc-Cdkn2aem2Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-190633

Cdkn2a(p19) gene knockout mouse model was established by knockout exon1 of Cdkn2a-p19ARF transcript (Cdkn2a-202 transcript).

Mice

Ythdf2-Flox

Strain Name：C57BL/6Smoc-Ythdf2em1(flox)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-CKO-190011

These mice carry loxP sites flanking exon3 of Ythdf2 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Ythdf2 gene.

Mice

Ythdf2-KO

Strain Name：C57BL/6Smoc-Ythdf2em2Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-190552

Exon 3 of Ythdf2 gene was deleted to generate Ythdf2 knockout mice.

Mice

Ythdf1-Flox

Strain Name：C57BL/6Smoc-Ythdf1tm1(flox)Smoc
Strain State：Repository Live | Cat. NO.：NM-CKO-190010

These mice carry loxP sites flanking exon3 of Ythdf1 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Ythdf1 gene.

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