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Models

About 181 results
Mice

Ilf2-KO

Strain Name:C57BL/6Smoc-Ilf2em1Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KO-190512

Exon 2-3 of Ilf2 gene was deleted to generate Ilf2 knockout mice.

Mice

C57BL/6

Strain Name:C57BL/6Smoc
Strain State:Repository Live | Cat. NO.:SM-001

C57BL/6 mice have a high reproductive capacity, a long life span, and a low tumor susceptibility. Male mice are aggressive and fight frequently. Diet can cause obesity, type II diabetes, and atherosclerosis in these mice. The C57BL/6 mouse is the first to have its entire genome sequenced. It is the most extensively used inbred mouse strain as a genetic basis for congenic and mutant mice. It is also used in genetics, metabolism, immunology, neurology, behavioral research, pharmacodynamics, and medication safety evaluation.

Mice

Trp53-KO

Strain Name:B6.129-Trp53tm1Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KO-00011

A neo cassette replaces exons 2-11,including the start codon,of Trp53 (transformation related protein 53).Null homozygotes show high, early-onset tumor incidence;some have persistent hyaloid vasculature and cataracts.

Mice

hTLR8/Lyz2-DTREGFP

Strain Name:C57BL/6Smoc-Lyz2em3(IRES-DTREGFP)Tlr8tm2(TLR8)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-200259

NM-KI-190041 was crossed with NM-HU-190044 to generate hTLR8/Lyz2-IRES-DTREGFP mice.

Mice

hPD-L1/hCD28

Strain Name:C57BL/6Smoc-Cd274em1(hPD-L1)Cd28em2(hCD28)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-210019

hPD-L1(NM-HU-00062) was crossed with hCD28(NM-HU-190011) to generate hPD-L1/hCD28 mice

Mice

hSIRPA/hCD47(BALB/c)

Strain Name:BALB/cAnSmoc-Sirpatm4(hSIRPA)/SmocCd47em1(hCD47)/Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-210020

hCD47 (NM-HU-00050) and hSRPA(2)(NM-HU-18015) were bred with BALB/c mice respectively to generate hSIRPA/hCD47(BALB/c) mice.

Mice

hPD-1/hIL1B

Strain Name:C57BL/6Smoc-Pdcd1em1(hPDCD1)Il1btm3(hIL1B)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-210018

hPD-1(NM-HU-00015) was crossed with hIL1B(NM-HU-190047) to generate hPD-1/hIL1B mice

Mice

hPD-1/hLAG3/hTIGIT

Strain Name:C57BL/6Smoc-Pdcd1em1(hPDCD1)Lag3em1(hLAG3)Tigitem1(hTIGIT)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-200258

hPD-1(NM-HU-00015),hTIGIT(NM-HU-00053) were crossed with hLAG3(NM-HU-00049) to generate hPD-1/hLAG3/hTIGIT.

Mice

hHLA-E

Strain Name:C57BL/6Smoc-Igs2em1(hHLA-E)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-200221

The endogenous human HLA-E gene (about 11kb) was knocked into the H11 locus via CRISPR/Cas9 mediated recombination.

Mice

R26-CAG-LSL-hMET-IRES-Luc-2A-tdTomato

Strain Name:C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-LSL-c-MET-IRES-luciferase-2A-tdTomato)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KI-18052

A SA-2xpolyA-CAG-Loxp-Stop-Loxp-human cMET-IRES-luciferase-2A-tdTomato-wpre-polyA cassette was knocked into the mouse Rosa26 locus . This strain of mice can be mated with mice expressing Cre recombinase so that human C-MET could be expressed after exposure to Cre recombinase.

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