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Models

About 167 results
Mice

Ilf2-KO

Strain Name：C57BL/6Smoc-Ilf2em1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-190512

Exon 2-3 of Ilf2 gene was deleted to generate Ilf2 knockout mice.

Mice

C57BL/6

Strain Name：C57BL/6
Strain State：Repository Live | Cat. NO.：SM-001
Validation Data：Presence

It was the first mouse strain to have its genome sequenced. With black coat color, it is recognized as the "standard" inbred strain and provides genetic background for numerous mutant genes. It is characterized by stable strain properties, ease of breeding, uniform stress responses, and high precision in experimental results.

Mice

Trp53-KO

Strain Name：B6.129-Trp53tm1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-00011

A neo cassette replaces exons 2-11,including the start codon,of Trp53 (transformation related protein 53).Null homozygotes show high, early-onset tumor incidence;some have persistent hyaloid vasculature and cataracts.

Mice

hTLR8/Lyz2-DTREGFP

Strain Name：C57BL/6Smoc-Lyz2tm3(IRES-DTREGFP)Tlr8tm2(TLR8)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-200259

NM-KI-190041 was crossed with NM-HU-190044 to generate hTLR8/Lyz2-IRES-DTREGFP mice.

Mice

hPD-L1/hCD28

Strain Name：C57BL/6Smoc-Cd274tm1(hPD-L1)Cd28tm2(hCD28)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-210019

hPD-L1(NM-HU-00062) was crossed with hCD28(NM-HU-190011) to generate hPD-L1/hCD28 mice

Mice

hSIRPA/hCD47(BALB/c)

Strain Name：BALB/cAnSmoc-Sirpatm4(hSIRPA)SmocCd47tm1(hCD47)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-210020
Validation Data：Presence

hCD47 (NM-HU-00050) and hSRPA(2)(NM-HU-18015) were bred with BALB/c mice respectively to generate hSIRPA/hCD47(BALB/c) mice.

Mice

hPD-1/hIL1B

Strain Name：C57BL/6Smoc-Pdcd1tm1(hPDCD1)Il1btm3(hIL1B)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-210018

hPD-1(NM-HU-00015) was crossed with hIL1B(NM-HU-190047) to generate hPD-1/hIL1B mice

Mice

hPD-1/hLAG3/hTIGIT

Strain Name：C57BL/6Smoc-Pdcd1tm1(hPDCD1)Lag3tm1(hLAG3)Tigittm1(hTIGIT)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-200258

hPD-1(NM-HU-00015),hTIGIT(NM-HU-00053) were crossed with hLAG3(NM-HU-00049) to generate hPD-1/hLAG3/hTIGIT.

Mice

hHLA-E

Strain Name：C57BL/6Smoc-Igs2tm1(hHLA-E)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-200221

The endogenous human HLA-E gene (about 11kb) was knocked into the H11 locus via CRISPR/Cas9 mediated recombination.

Mice

R26-CAG-LSL-hMET-IRES-Luc-2A-tdTomato

Strain Name：C57BL/6Smoc-Gt(ROSA)26Sortm1(CAG-LSL-c-MET-IRES-luciferase-2A-tdTomato)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-18052

A SA-2xpolyA-CAG-Loxp-Stop-Loxp-human cMET-IRES-luciferase-2A-tdTomato-wpre-polyA cassette was knocked into the mouse Rosa26 locus . This strain of mice can be mated with mice expressing Cre recombinase so that human C-MET could be expressed after exposure to Cre recombinase.

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