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Models

About 197 results
Mice

Pfkp-KO

Strain Name：C57BL/6Smoc-Pfkpem1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-190555

Pde4d-KO mice (Stock No.NM-KO-190555） carry a knockout allele derived from the targeted deletion of exon 4.

Mice

Cadm1-KO(2)

Strain Name：C57BL/6Smoc-Cadm1em2Smoc
Strain State：Repository Live | Cat. NO.：NM-KO-200593

Cadm1-KO(2) mice (Stock No.NM-KO-200593） carry a knockout allele derived from the targeted deletion of exon 6. While Cadm1-KO mice (Stock No.NM-KO-200078) have been pulled from shelves for some reasons.

Mice

H11-CAG-LSL-Myc

Strain Name：C57BL/6Smoc-Igs2em1(CAG-LSL-Myc)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-00039
Validation Data：Presence  |  Publications：2piece

The c-Myc gene (also known as Myc) is abnormally expressed in many tumors and plays a critical role in the regulation of cell proliferation, growth and metabolism, gene instability, stimulation of angiogenesis, malignant transformation, cell differentiation and apoptosis. These mice harbor a loxP-flanked STOP cassette preventing transcription of a CAG promoter-driven Myc oncogene. The targeted mutation was inserted into the Hipp11(H11) locus by homologous recombination. Myc is expressed when bred to mice that express Cre recombinase.

Mice

Fcgr2b-KO(3)

Strain Name：C57BL/6Smoc-Fcgr2bem1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-210279
Validation Data：Presence

Fcgr2b-KO(3) mice (Stock No.NM-KO-210279）carry a knockout allele derived from the targeted deletion of exon 3-5.Fcgr2b-KO mice (Stock No.NM-KO-00130）carry a knockout allele derived from the targeted deletion of exon 3. Fcgr2b-KO(2) mice (NM-KO-191214） have been pulled from shelves for some reasons.

Mice

Cth-Luc

Strain Name：B6;129S-Cthtm1(Luc)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-00004

Cth was targeted by insertion of a floxed Luciferase gene and an frt-neo-frt cassette before exon 1. These mice have normal development and fertility.

Mice

Cxcr5(702bp)-KO

Strain Name：C57BL/6Smoc-Cxcr5em4Smoc
Strain State：Repository Live | Cat. NO.：NM-KO-252191

These strains carry a targeted deletion in intron 2 of the Cxcr5 gene.

Mice

Prrx1-KO

Strain Name：C57BL/6Smoc-Prrx1em1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-00165

Exon1 of Prrx1 gene was targeted to generate Prrx1 knockout mice.

Mice

Atg5-KO

Strain Name：C57BL/6Smoc-Atg5em2Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-18004

Exon3 of Atg5 gene was targeted and a additional 58bp sequence insertion caused a frameshift mutation.

Mice

Trpv6-KO

Strain Name：B6;129S-Trpv6tm1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-00168

Exon2 of Trpv6 gene was targeted to generate Trpv6 knockout mice.

Mice

Il1f6-KO

Strain Name：C57BL/6Smoc-Il1f6em1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-00097

Exon2-3 of Il1f6 gene were targeted to generate Il1f6 knockout mice.

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