Welcome to Advanced Search

Shanghai Model Organisms Jinshan R&D Base officially put into operation

Shanghai Model Organisms

After the base is put into operation, SMOC’s capability to provide genetically modified rat/mouse models and technical services including gene function research and drug development will be greatly enhanced.

Shanghai Model Organisms Center Inc has licensed CRISPR-Cas9 technology from Broad Institute

CRISPR-Cas9 technology Broad Institute genetically modified mouse

On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.

SMOC Received OLAW (Office of Laboratory Animal Welfare) Approval for Animal Welfare Assurance

Shanghai Model Organisms Center Inc.(SMOC) received the approval of Animal Welfare Assurance from the Office of Laboratory Animal Welfare (OLAW) of the U.S. National Institutes of Health (NIH) for its animal facility on January 25, 2021.

"Biomodel Organism" Holds Ceremony in Beijing to Celebrate Listing on NEEQ

On November 18, 2016, Shanghai Model Organisms Center, Inc. was listed on the NEEQ as follows. Stock Name: Biomodel Organism; Stock Code: 839728.

SMOC Launched U-HuDTMbase®, Inclusive Resource Library of Innovative Therapeutic Target-Humanized Mouse Models, to Accelerate Novel Drug Discovery

U-HuDTMbase® is composed of more than 600 therapeutic target-humanized mouse models, including multiple background strains, and has covered almost all commonly studied areas, such as oncology, metabolism, immunity, inflammation and more.

Milestones

Our vision is to provide researchers all over the world with comprehensive, convenient and professional animal model services to facilitate a simplified and highly-efficient approach towards uncovering the mysteries of life.

Workshop：Progress and Advances in Preclinical immuno-Oncology Research

SMOC’s Annual Progress and Advances in Preclinical immuno-Oncology Research: The workshop is designed as a forum for ideas and opinions exchange on how to decrease the rate of clinical failures in oncology and immuno-oncology.

On Nature Genetics Prof. Bin Zhou's group used lineage-tracing mice produced by SMOC to investigate the role of bronchioalveolar stem cells

bronchioalveolar stem cells lung repair lung regeneration

Published on today's Nature Genetics, Prof. Bin Zhou's research group from Shanghai Institute of Biochemistry and Cell Biology revealed the bona fide role of bronchioalveolar stem cells (BASC) during lung repair and regeneration.

Disease Mouse Models (Non-genetically-engineered)

diseases mice diseases model non genetically modified organisms

Shanghai Model Organisms has established a library of typical mouse models of human diseases through surgery or drug induction, thereby providing useful animal models for the research on pathogenesis of related diseases, functional studies of genes or proteins in diseases, screening of disease drugs and evaluation of therapeutic effects, etc.

Model Repository

model repository

Shanghai Model Organisms has established more than 18,000 genetically modified mouse models using three core technologies of gene editing. It has more than 10,000 proprietary genetically engineered mouse models that can be directly used for studies on gene functions, drug screening, and human diseases. At the same time, Shanghai Model Organisms has more than 30 fluorescent-labeled tumor cell lines, which can be used for in vitro experiments, studies on tumor bearing mice and other tumor researches.