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R26-CAG-Loxp-tdTomato-Loxp-EGFP(SD)

Strain Name：SD-Gt(ROSA)26Sor^{em1(CAG-Loxp-tdTomato-3xpolyA-Loxp-EGFP)Smoc} Strain State：Repository Live | Cat. NO.：NR-KI-190007

These rats harbor a CAG-Loxp-tdTomato-3xpolyA-Loxp-EGFP cassette in the Rosa26 locus generated by homologous recombination.

R26-CAG-LSL-Cas9-IRES-tdTomato(SD)

Strain Name：SD-Gt(ROSA)26Sor^{em1(CAG-LSL-Cas9-FRT-IRES-tdTomato-FRT-WPRE-polyA)Smoc} Strain State：Repository Live | Cat. NO.：NR-KI-200004

These rats harbor a CAG-LSL-Cas9-FRT-IRES-tdTomato-FRT-WPRE-polyA cassette in the Rosa26 locus generated by homologous recombination.

CT26-Rosa26-hFOLR1/hCD47

Strain Name：CT26-Gt(ROSA)26Sor^{em1(hFOLR1/hCD47)Smoc}
Strain State ： Validation of target gene expression completed |  Cat. NO.：NMC-230025

FOLR1/CD47 gene humanized MC38 cell line

Gene overexpression

gene overexpression gene overexpression protocol gene overexpression techniques

Generate a mouse model in which an exogenous gene is introduced and overexpressed. An overexpression model can be used to investigate gene functions, promoter functions, or model the pathogenesis of human disease. Depending on the method to introduce foreign DNA, a random transgenes or targeted conditional overexpression model can be created.

Lineage tracing

lineage tracing genetic lineage tracing genetic fate mapping

Genetic lineage tracing is a commonly used and the most effective method for studying the origin and fate of specific cell types. The construction of genetically engineered mouse model is the most important step in the lineage tracing technique.

Gene tracking

marker gene gene tracking

Gene tracers are an important application for genetically engineered mice. Through gene knock-in, exogenous tracer genes were knocked into endogenous genes, enabling labeling and tracing of genes.

Type of genetic engineering

genetic modified organism types of genetic engineering genetic engineering technology

Three types of genetic modification by the gene engineered technology: gene knockout. gene knock-in, gene overexpression.

GEMM-Derived Allografts

Study of Gene Functions

gene functions methods to study gene function what are the functions of genes