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CKO mice developed by SMOC supported the identification of a novel lncRNA that regulates dendritic cell migration and the corresponding immune response

CKO mice lncRNA dendritic cell

These Mice Are About to Go Viral Because of the Nobel Prize!

microRNA (miRNA) microRNA mouse models Nobel Prize microRNA discovery genetically engineered mice miRNA in gene regulation miRNA therapeutics miRNA in cancer research customized mouse models contract research organization (CRO) preclinical drug discovery

The 2024 Nobel Prize in Physiology or Medicine awarded to Victor Ambros and Gary Ruvkun for their discovery of microRNA (miRNA) highlights its revolutionary role in gene regulation and disease treatment. This article explores miRNA's impact on neuroscience, cancer, and cardiovascular research. GenoBioTX offers advanced microRNA mouse models and customized genetic solutions, empowering researchers with essential tools to drive innovation in miRNA studies and therapeutic developments.

SMOC Launched U-HuDTMbase®, Inclusive Resource Library of Innovative Therapeutic Target-Humanized Mouse Models, to Accelerate Novel Drug Discovery

U-HuDTMbase® is composed of more than 600 therapeutic target-humanized mouse models, including multiple background strains, and has covered almost all commonly studied areas, such as oncology, metabolism, immunity, inflammation and more.

Enhancing Your Research: How GenoBioTX's Gene Editing Technology Empowers Research Breakthroughs

Gene editing technology GenoBioTX seminar Genome editing platform Gene regulation Gene editing techniques Biotechnology seminar Preclinical research tools.

This seminar will introduce GenoBioTX’s gene editing platform and technology, highlighting how these techniques can enhance your research projects. We will cover the history of genome editing, provide an overview of GenoBioTX’s gene editing platform and technology, and present case studies that demonstrate how our gene editing techniques can facilitate research advancements.

Metabolic Analysis

Metabolic analysis

There are many mice models used to mimic human metabolic diseases, such as diabetes and obesity, which are caused by nutritional imbalances and metabolic disorders. The detection and analysis of sugar and lipid metabolism phenotypes in these model mice are crucial for the establishment of model mice, the study of disease progression, and the research on the pathogenesis. Shanghai Model Organisms can help your research on metabolism by providing you with a series of testing tools for glucose and lipid metabolisms.

Phenotyping

mouse phenotype mouse phenotype database gene phenotype

Provide blood analysis, image analysis, pathology analysis, behavior analysis etc.

表現型分析

血液検査、画像分析、組織病理形態学的分析、行動学的研究、代謝学的分析などを提供することができます。

표현형 분석

혈액 검사, 영상 분석, 조직 병리 형태 분석, 행동 연구, 대사 분석 등을 제공합니다.

Mouse

transgenic mice mouse model editing mouse

Mice have long been the prime choice for model organisms. In more than 100 years, mice have been widely used by researchers in the fields of physiology, pathology, pharmacology, toxicology, and behavioral science. With the establishment of gene targeting technology, many researchers have made their way to the Nobel Prize.

Services

genetic engineering genetic animals genetic engineering examples

Shanghai Model Organisms offers a full range of model organism services, including model customization services, research-ready models, breeding, phenotyping and drug screening. Mouse, rat, zebrafish and C. elegans models are available to meet different research needs.