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Models

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Mice

R26-CAG-LSL-hEGFR*L858R/T790M/C797S-IRES-Luc-2A-tdTomato

Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-LSL-EGFR (L858R-T790M-C797S)-IRES-luciferase-2A-tdTomato)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-190067

These mice harbor a CAG-LSL-EGFR (L858R-T790M-C797S)-IRES-luciferase-2A-tdTomato cassette in the Rosa26 locus generated by homologous recombination.

Mice

R26-CAG-LSL-hEML4/ALK*F1174L-Luc-tdTomato

Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem1(SA-2xpolyA-CAG-LSL-EML4-ALK(F1174L)-IRES-luciferase-2A-tdTomato)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-190010

A SA-2xpolyA-CAG-LSL-EML4-ALK(F1174L)-IRES-Luciferase-2A-tdTomato-WPRE-polyA cassette was inserted at the Rosa26 locus. When bred to a strain expressing Cre recombinase under control of various tissue specific promoters, Cre recombination deletes the LSL cassette and allows the expression of the EML4-ALK(F1174L) protein.

Mice

Stk11-Flox/R26-CAG-LSL-Luc-2A-EGFP

Strain Name：C57BL/6Smoc-Stk11tm1(flox)Gt(ROSA)26Sorem1(CAG-LSL-Luciferase-2A-EGFP-wpre-polyA)Smoc
Strain State：Repository Live | Cat. NO.：NM-CKO-234717

The Stk11-Flox(NM-CKO-18014) was crossed with R26-CAG-LSL-Luc-2A-EGFP(NM-KI-190095) to generate Stk11-Flox/R26-CAG-LSL-Luc-2A-EGFP mice.

Mice

Stk11-Flox/R26-CAG-LSL-Luc-2A-EGFP/Kras-LSL-G12D

Strain Name：C57BL/6Smoc-Stk11tm(flox)1Gt(ROSA)26Sorem1(CAG-LSL-Luciferase-2A-EGFP-wpre-polyA)Krasem4(LSL-G12D)Smoc
Strain State：Repository Live | Cat. NO.：NM-CKO-234719

The Stk11-Flox/R26-CAG-LSL-Luc-2A-EGFP(NM-CKO-234717) was crossed with Kras-LSL-G12D(NM-KI-190003) to generate Stk11-Flox/R26-CAG-LSL-Luc-2A-EGFP/Kras-LSL-G12D mice.

Mice

Kras-LSL-G12D/R26-CAG-LSL-Luc-2A-EGFP/hKLKB1

Strain Name：C57BL/6Smoc-Krasem4(LSL-G12D)Gt(ROSA)26Sorem(CAG-LSL-Luciferase-2A-EGFP-wpre-polyA)Klkb1tm1(hKLKB1)Smoc
Strain State：Developing | Cat. NO.：NM-XA-234940

The Kras-LSL-G12D/R26-CAG-LSL-Luc-2A-EGFP(NM-KI-234718) was crossed with hKLKB1(NM-HU-225076) to generate Kras-LSL-G12D/R26-CAG-LSL-Luc-2A-EGFP/hKLKB1 mice.

Mice

Kras-LSL-G12D/R26-CAG-LSL-Luc-2A-EGFP

Strain Name：C57BL/6Smoc-Krasem4(LSL-G12D)Gt(ROSA)26Sorem1(CAG-LSL-Luciferase-2A-EGFP-wpre-polyA)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-234718

The Kras-LSL-G12D(NM-KI-190003) was crossed with R26-CAG-LSL-Luc-2A-EGFP(NM-KI-190095) to generate Kras-LSL-G12D/R26-CAG-LSL-Luc-2A-EGFP mice.

Mice

Rb1-Flox/Trp53-Flox/R26-CAG-LSL-Luc-2A-EGFP

Strain Name：C57BL/6Smoc-Rb1tm1(flox)Trp53tm2(flox)Gt(ROSA)26Sorem1(CAG-LSL-Luciferase-2A-EGFP-wpre-polyA)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-234513

The Rb1-Flox/Trp53-Flox(NM-CKO-232461) was crossed with R26-CAG-LSL-Luc-2A-EGFP(NM-KI-190095) to generate Rb1-Flox/Trp53-Flox/R26-CAG-LSL-Luc-2A-EGFP mice.

Mice

Rbl2-Flox/Rb1-Flox/Trp53-Flox/R26-CAG-LSL-Luc-2A-EGFP

Strain Name：C57BL/6Smoc-Rbl2tm1(flox)Rb1tm1(flox)Trp53tm2(flox)Gt(ROSA)26Sorem1(CAG-LSL-Luciferase-2A-EGFP-wpre-polyA)Smoc
Strain State：Repository Live | Cat. NO.：NM-CKO-234596

The Rbl2-Flox(NM-CKO-200029) was crossed with Rb1-Flox/Trp53-Flox/R26-CAG-LSL-Luc-2A-EGFP(NM-KI-234513) to generate Rbl2-Flox/Rb1-Flox/Trp53-Flox/R26-CAG-LSL-Luc-2A-EGFP mice.

Mice

Il1b-Luc-2A-EGFP

Strain Name：C57BL/6Smoc-Il1bem1(Luc-eGFP)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-00010

A Luciferase-2A-EGFP-pA cassette was inserted at ATG site of mouse Il1b gene. The intrisic promoter drives the expression of reporter genes, which reflects the activity of Il1b.

Mice

Il11-Luc-2A-EGFP

Strain Name：C57BL/6Smoc-Il11em1(Luc-eGFP)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-00036

A Luciferase-2A-EGFP-pA cassette was inserted after ATG the start codon. The intrisic promoter drives the expression of reporter genes, which reflects the activity of Il11.

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