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Models

About 72 results
Mice

Irf5-Flox

Strain Name：C57BL/6Smoc-Irf5em1(flox)Smoc
Strain State：Repository Live | Cat. NO.：NM-CKO-200191

These mice carry loxP sites flanking exon 2 of Irf5 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Irf5 gene.

Mice

Ranbp2-Flox

Strain Name：C57BL/6Smoc-Ranbp2tm1(flox)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-CKO-200030

These mice carry loxP sites flanking exon 3 of Ranbp2 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Ranbp2 gene.

Mice

Agt-KO

Strain Name：C57BL/6Smoc-Agtem1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-190740

Exon 2-5 of Agt gene was deleted to generate Agt knockout mice.

Mice

Sec31a-KO

Strain Name：C57BL/6Smoc-Sec31aem1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-200470

Exon 3 of Sec31a gene was deleted to generate Sec31a knockout mice.

Mice

Il2-KO

Strain Name：C57BL/6Smoc-Il2em2Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-190486

Exon 3 of Il2 gene was deleted to generate Il2 knockout mice.

Mice

Stat3-Flox(2)

Strain Name：C57BL/6Smoc-Stat3em1(flox)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-CKO-200225

These mice carry loxP sites flanking exon 18-20 of Stat3 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Stat3 gene.While Stat3-Flox(Stock No.NM-CKO-200050）mice carrying the loxP sites flanking exon 12-14 of Stat3 gene.

Mice

Il1b-Luc-Tg

Strain Name：B6.Cg-Tg(IL1B-luc)Smoc
Strain State：Repository Live | Cat. NO.：NM-TG-00001

The transgenic mice model could be used to study transcriptional regulation of the IL-1βgene expression in the inflammatory process and evaluation the effect of anti-inflammatory drug in vivo.

Mice

Il17a-Cre

Strain Name：C57BL/6Smoc-Il17aem1(iCre-polyA(SV40))Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200137

A iCre-polyA expression cassette was knocked into the Il17a gene start codon site. This gene encodes a pro-inflammatory cytokine that is a member of the interleukin-17 family. When crossed with a strain carrying a gene flanked by loxP sites, the flanked gene will be removed in cells expressing cre. This strain may be useful for studying autoimmune inflammatory diseases such as rheumatoid arthritis, psoriasis and multiple sclerosis.

Mice

Vip-IRES-Cre

Strain Name：C57BL/6Smoc-Vipem1(IRES-iCre-SV40-pA)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200100

A IRES-iCre expression cassette was knocked into the Vip gene stop codon site. Vip encodes vasoactive intestinal polypeptide. When crossed with a strain carrying a gene flanked by sites, the flanked gene will be removed in cells expressing. This strain is useful for studying bronchiectasis, immunomodulatory and anti-inflammatory.

Mice

Il13-IRES-Cre

Strain Name：C57BL/6Smoc-Il13em1(IRES-iCre)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-200166

A IRES-iCre expression cassette was knocked into the Il13 gene stop codon site. This gene encodes a multifunctional cytokine. When crossed with a strain carrying a gene flanked by loxP sites, the flanked gene will be removed in cells expressing cre. This cytokine participates in the regulation of immune response, inflammatory response and hematopoietic process.

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