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Models

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Mice

Mir29b2/Mir29c-KO

Strain Name：C57BL/6Smoc-Mir29b-2em1 Mir29cem1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-00080

Mir29b-2 and Mir29c are located in 3'UTR region of Cd46 gene. a 0.7kb region in length including Mir29b-2 and Mir29c pre-microRNAs was removed in this strain.

Mice

Cxcr5(702bp)-KO

Strain Name：C57BL/6Smoc-Cxcr5em4Smoc
Strain State：Repository Live | Cat. NO.：NM-KO-252191

These strains carry a targeted deletion in intron 2 of the Cxcr5 gene.

Mice

Fah-KO(Rag2/IL2rg-KO/hSIRPA(2)/hCD47)

Strain Name：C57BL/6Smoc-Sirpaem1(hSIRPA)Cd47em1(hCD47)Rag2em1Il2rgem1Fahem1Smoc
Strain State：Developing | Cat. NO.：NM-KO-254190

By deleting exon 8 of the Fah gene in the existing strain Rag2/IL2rg-KO/hSIRPA(2)/hCD47 (NM-HU-2000019), a Fah gene knockout mouse model was established.

Mice

R26-CAG-KikGR(2)

Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-Kozak-KikGR-WPRE-pA)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-XA-242128

These mice harbor a CAG-KikGR-WPRE-pA cassette in the Rosa26 locus generated by homologous recombination

Mice

hLDLR-delta ARE

Strain Name：C57BL/6Smoc-hLDLRtm1(delta ARE)Smoc
Strain State：Developing | Cat. NO.：NM-HU-253731

This product was derived by deleting a certain region in the 3'UTR part based on the NM-HU-230148 (hLDLR) mice.

Mice

R26-U6-Luc3.12 gRNA-CAG-Cas13d

Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem1(U6-Luc3.12 gRNA-CAG-Cas13d)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-200265

These mice harbor a U6-Luc3.12 gRNA-CAG-Cas13d cassette in the Rosa26 locus generated by homologous recombination.

Mice

R26-U6-mcherry gRNA-CAG-Cas13b

Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem1(U6-mcherry gRNA-CAG-Cas13b)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-200266

These mice harbor a U6-mcherry gRNA-CAG-Cas13b cassette in the Rosa26 locus generated by homologous recombination.

Mice

R26-U6-mcherry gRNA-CAG-Cas13d

Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem1(U6-mcherry gRNA-CAG-Cas13d)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-200268

These mice harbor a U6-mcherry gRNA-CAG-Cas13d cassette in the Rosa26 locus generated by homologous recombination.

Mice

R26-U6-Luc3.12 gRNA-CAG-Cas13b

Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem1(U6-Luc3.12 gRNA-CAG-Cas13b)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-200264

These mice harbor a U6-Luc3.12 gRNA-CAG-Cas13b cassette in the Rosa26 locus generated by homologous recombination.

Mice

BALB/c

Strain Name：BALB/cAnSmoc
Strain State：Repository Live | Cat. NO.：SM-003

BALB/c is one of the most widely used inbred lines in biomedical research, especially in immunology and infectious disease research. The incidence of breast tumors is about 10% to 20%. There is a certain number of ovarian, adrenal, pulmonary tumors, and leukemia that occurs. Lung cancer occurs in 26% of female mice and 29% of male mice. The incidence of leukemia is 12% in females and 10% in males. Blood pressure was the highest compared to other inbred mice and had spontaneous hypertension.

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