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Models

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Mice

Stat3-KO(in-frame mutation)

Strain Name：C57BL/6Smoc-Stat3emSmoc
Strain State：Repository Live | Cat. NO.：NM-KO-210186

exon 18-20 of Stat3 gene was deleted to generate Stat3 knockout mice. The targeted knockout region mirrors that of the NM-CKO-200225 strain, with the experimental strategy designed according to published methodologies (PMID: 14566054; 17660847; 12571365).Lethality associated with this genetic modification has been documented. For details, click on the MGI ID in the genetic information.

Mice

hAHR

Strain Name：C57BL/6Smoc-Ahrem1(hAHR)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-200252

The endogenous mice Ahr gene was replaced by human AHR gene.

Mice

Ahr-KO

Strain Name：C57BL/6Smoc-Ahrem1Smoc
Strain State：Repository Live | Cat. NO.：NM-KO-18008

Exon3 of Ahr gene was deleted to generate Ahr knockout mice. The homozygous female mice of this strain had impaired fertility. There have been reports of deaths caused by genetic modification. For details, click on the MGI ID in the genetic information.

Mice

Ahr-Flox

Strain Name：C57BL/6Smoc-Ahrem1(flox)Smoc
Strain State：Repository Live | Cat. NO.：NM-CKO-200060

These mice carry loxP sites flanking exon 2 of Ahr gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Ahr gene.

Mice

Dpp6-Flox

Strain Name：C57BL/6Smoc-Dpp6em1(flox)Smoc
Strain State：Developing | Cat. NO.：TBD

These mice carry loxP sites flanking target exons of Dpp6 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Dpp6 gene.

Mice

Dpp6-KO

Strain Name：C57BL/6Smoc-Dpp6em1Smoc
Strain State：Repository Live | Cat. NO.：NM-KO-251757

The exon 2 of Dpp6 gene was deleted to generate Dpp6 knockout mouse.

Mice

Epha1-KO

Strain Name：C57BL/6Smoc-Epha1em1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-191127

Exon 2 of Epha1 gene was deleted to generate Epha1 knockout mice.

Mice

Tead2-KO

Strain Name：C57BL/6Smoc-Tead2em1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-191049

Exon 3-4 of Tead2 gene was deleted to generate Tead2 knockout mice.

Mice

Itga1-KO

Strain Name：C57BL/6Smoc-Itga1em1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-190717

Exon 6 of Itga1 gene was deleted to generate Itga1 knockout mice.

Mice

Ccnd3-KO

Strain Name：C57BL/6Smoc-Ccnd3em1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-190726

Exon 4-5 of Ccnd3 gene was deleted to generate Ccnd3 knockout mice.

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