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Models

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Mice

Foxp3-IRES-tdTomato-2A-Cre

Strain Name:C57BL/6Smoc-Foxp3em3(IRES-tdTomato-2A-iCre)Smoc
Strain State:Repository Live | Cat. NO.:NM-KI-190119

A IRES-tdTomato-2A-Cre expression cassette was knocked into the Foxp3 gene stop codon site. This strain is useful in studying regulatory T cell in autoimmunity, especially in type 1 diabetes.

Mice

Clu-2A-DreERT2

Strain Name:C57BL/6Smoc-Cluem2(2A-DreERT2)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KI-200025

A 2A-DreERT2 expression cassette was knocked into the Clu gene stop codon site.

Mice

R26-CAG-LSL-hEML4/ALK*F1174L-Luc-tdTomato

Strain Name:C57BL/6Smoc-Gt(ROSA)26Sorem1(SA-2xpolyA-CAG-LSL-EML4-ALK(F1174L)-IRES-luciferase-2A-tdTomato)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KI-190010

A SA-2xpolyA-CAG-LSL-EML4-ALK(F1174L)-IRES-Luciferase-2A-tdTomato-WPRE-polyA cassette was inserted at the Rosa26 locus. When bred to a strain expressing Cre recombinase under control of various tissue specific promoters, Cre recombination deletes the LSL cassette and allows the expression of the EML4-ALK(F1174L) protein.

Mice

Ucp1-Cre

Strain Name:C57BL/6Smoc-Ucp1em2(Kozak-Cre-WPRE-pA)Smoc
Strain State:Repository Live | Cat. NO.:NM-KI-190105

A Kozak-Cre-WPRE-pA expression cassette was knocked into the Ucp1 gene start codon site.

Mice

Il4-Luc-2A-EGFP

Strain Name:C57BL/6Smoc-Il4em1(Luc-eGFP)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KI-00021

A Luciferase-2A-EGFP-pA cassette was inserted after ATG the start codon.The intrisic promoter drives the expression of reporter genes, which reflects the activity of Il4.

Mice

Nkx2-5-IRES-Cre

Strain Name:C57BL/6Smoc-Nkx2-5em1(IRES-Cre-WPRE-polyA)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KI-200152

A IRES-Cre-WPRE-polyA expression cassette was knocked into the Nkx2-5 gene stop codon site.

Mice

Myh11-2A-DreERT2

Strain Name:C57BL/6Smoc-Myh11em1(2A-DreERT2)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KI-190037

A 2A-DreERT2 expression cassette was knocked into the Myh11 gene stop codon site.

Mice

Slc17a6-IRES-Cre

Strain Name:C57BL/6Smoc-Slc17a6em1(IRES-iCre)Smoc
Strain State:Repository Live | Cat. NO.:NM-KI-200087

A IRES-iCre expression cassette was knocked into the Slc17a6 gene stop codon site.

Mice

Pax7-IRES-CreERT2

Strain Name:C57BL/6Smoc-Pax7em1(IRES-Cre-ERT2)Smoc
Strain State:Repository Live | Cat. NO.:NM-KI-200099

A IRES-Cre-ERT2 expression cassette was knocked into the Pax7 gene stop codon site. Pax7 is expressed in myogenic progenitor cells. Pax7 is essential for the myogenic potential, survival, and proliferation of myogenic progenitors. When crossed with a strain carrying a gene flanked by loxP sites, the flanked gene will be removed in cells expressing Pax7 after tamoxifen treatment.

Mice

Lyz2-IRES-mtagBFP2-Luc

Strain Name:C57BL/6Smoc-Lyz2em4(IRES-mtagBFP-Luci)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KI-200029

A IRES-mtagBFP-luci expression cassette was knocked into the Lyz2 gene stop codon site.

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