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Models

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Mice

Mcpt8-2A-CreERT2

Strain Name：C57BL/6Smoc-Mcpt8em1(2A-CreERT2-WPRE-polyA)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-200006
Validation Data：Presence

A 2A-CreERT2-WPRE-polyA expression cassette was knocked into the Mcpt8 gene stop codon site.

Mice

Ifng-Venus-Luc

Strain Name：C57BL/6Smoc-Ifngem1(IRES-Venus-Luci)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-18041
Validation Data：Presence

An IRES-Venus-Luci co-expression cassette was inserted in 3'UTR region of Ifng gene.

Mice

Col1a1-TRE3G-dCas9-VPR-EGFP

Strain Name：C57BL/6Smoc-Col1a1em1(TRE3G-dCas9-VPR-eGFP-pA)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-00123

These mice harbor a TRE3G-dCas9-VPR(VP64-p65-Rta)-eGFP-pA tetracycline-controlled transcriptional activation cassette in mouse Col1a1 loci. This strain can be used in CRISPR mediated target gene transcriptional activation (CRISPRa).

Mice

Il12a-Luc-2A-EGFP

Strain Name：C57BL/6Smoc-Il12aem1(Luc-eGFP)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-00024

A Luciferase-2A-EGFP-pA cassette was inserted after ATG the start codon. The intrisic promoter drives the expression of reporter genes, which reflects the activity of Il12a.

Mice

Mnx1-2A-CreERT2

Strain Name：C57BL/6Smoc-Mnx1em1(2A-CreERT2-WPRE-polyA)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200009
Validation Data：Presence

A 2A-CreERT2-WPRE-polyA expression cassette was knocked into the Mnx1 gene stop codon site.

Mice

Il16-Luc-2A-EGFP

Strain Name：C57BL/6Smoc-Il16em1(Luc-eGFP)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-00028

A Luciferase-2A-EGFP-pA cassette was inserted after ATG the start codon. The intrisic promoter drives the expression of reporter genes, which reflects the activity of Il16.

Mice

hPD-1/hVISTA

Strain Name：C57BL/6Smoc-Visrtm1(hVSIR)Pdcd1tm1(hPDCD1)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000092

hPD-1(NM-HU-00015) was crossed with hSIRPA(2) (NM-HU-18015) to generate hPD-1/hVISTA.

Mice

Esr1-2A-Cre

Strain Name：C57BL/6Smoc-Esr1em1(2A-iCre)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-200164
Validation Data：Presence

A 2A-iCre expression cassette was knocked into the Esr1 gene stop codon site.

Mice

Foxp3-V5-AviTag-IRES-Luc-2A-tdTomato

Strain Name：C57BL/6Smoc-Foxp3em1(V5-AviTag-IRES-luci-2A-tdTomato)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-18034

A V5-AviTag-IRES-luci-2A-tdTomato expression cassette was inserted before the stop codon TGA of mouse Foxp3 gene to establish a multi-labeled knockin model with V5, Avi, luciferase and tdTomato fluorescent protein.

Mice

Itgam-IRES-DTRGFP

Strain Name：C57BL/6Smoc-Itgamem1(IRES-DTR-EGFP)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200066
Validation Data：Presence

A IRES-DTR-EGFP expression cassette was knocked into the Itgam gene stop codon site.

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