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Mice

Tie1-2A-Cre

Strain Name：C57BL/6Smoc-Tie1em1(2A-Cre)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-18023

A 2A-Cre coexpression cassette is inserted befor the stop codon of mouse Tie1 gene via homologous recombination to establish a tamoxifen inducible Tie1-Cre tool stain. This strain can be used to knockout target gene in Tie1+ cells when crossed with mice which carry loxp sites flanking target gene.

Mice

Wnt1-Dre

Strain Name：C57BL/6Smoc-Wnt1em1(Dre-Wpre-polyA)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-200176

A Dre-Wpre-polyA expression cassette was knocked into the Wnt1 gene start codon site. Wnt1 gene is involved in stem cell poliferation in multiple systems, including the hematopoietic system and the embryonic nervous system. This strain may be useful for studying central nervous system development. When crossed with a strain carrying a gene flanked by rox sites, the flanked gene will be removed in cells expressing dre.

Mice

Cd19-2A-DreERT2

Strain Name：C57BL/6Smoc-Cd19em(2A-DreERT2-Wpre-pA)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-215084

2A-DreERT2-Wpre-pA expression cassette was knocked into the Cd19 gene .

Mice

Tnnt2-dCreERT2

Strain Name：C57BL/6Smoc-Tnnt2em1(rox-CreERT2-wpre-polyA-rox-tdTomato-wpre-polyA)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-200015

A rox-CreERT2-wpre-polyA-rox-tdTomato-wpre-polyA expression cassette was knocked into the Tnnt2 gene start codon site.

Mice

hCRLF2

Strain Name：C57BL/6Smoc-Crlf2tm1(hCRLF2)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-210028

The endogenous mice Crlf2 gene was completely or partially replaced by human CRLF2 gene via ESC targeting.

Mice

hPD-L1/hSIGLEC15

Strain Name：C57BL/6Smoc-Cd274em1(hCD274)Siglec15em1(hSIGLEC15)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000103

hPD-L1(NM-HU-00062) was crossed with hSIGLEC15(NM-HU-190037) to generate hPD-L1/hSIGLEC15.

Mice

Foxn1-IRES-Cre

Strain Name：C57BL/6Smoc-Foxn1em1(IRES-iCre)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-200106

A IRES-iCre expression cassette was knocked into the Foxn1 gene stop codon site. The protein encoded by Foxn1 (forkhead box N1) gene is part of the forkhead family or transcription factors that are important in developmental processes, immune system regulation, metabolism, cancer and aging. When crossed with a strain carrying a gene flanked by sites, the flanked gene will be removed in thymic epithelial cell and keratinocytes.

Mice

Il17c-Luc-2A-EGFP

Strain Name：C57BL/6Smoc-Il17cem1(Luc-eGFP)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-00030

A Luciferase-2A-EGFP-pA cassette was inserted after ATG the start codon. The intrisic promoter drives the expression of reporter genes, which reflects the activity of Il17c.

Mice

Cela1-2A-DreERT2

Strain Name：C57BL/6Smoc-Cela1em1(2A-DreERT2)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-190094

A 2A-DreERT2 expression cassette was knocked into the Cela1 gene stop codon site.

Mice

Itgax-2A-DreERT2

Strain Name：C57BL/6Smoc-Itgaxem1(2A-DreERT2)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-190032

A 2A-DreERT2 expression cassette was knocked into the Itgax gene stop codon site.

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