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Models

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Mice

Tert-CreERT2-2A-EGFP

Strain Name:C57BL/6Smoc-Tertem1(CreERT2-2A-GFP-WPRE-PA)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KI-18037

A CreERT2-2A-GFP-WPRE-PA expression cassette was knocked into the Telt gene start codon site by homologous recombination.

Mice

Il17a-2A-CreERT2

Strain Name:C57BL/6Smoc-Il17aem1(2A-CreERT2)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KI-00059

A 2A-Cre cassette was inserted before stop codon of mouse Il17a gene which is known as a T cell marker.

Mice

hIL4/hIL4R

Strain Name:C57BL/6Smoc-Il4tm3(hIL4)Il4ratm1(hIL4R)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-2000106

These mice are obtained through breeding of two single gene humanized mice.

Mice

R26-CAG-2xKRAB-dCas9-IRES-EGFP

Strain Name:C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-Loxp-2xKRAB-dCas9-IRES-EGFP)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KI-18007

These mice harbor a CAG-LSL-2xKRAB-dCas9-IRES-EGFP-WPRE-pA conditional expression cassette in mouse Rosa26 loci via homologous recombination. This strain can be used in CRISPR mediated target gene transcriptional inhibition (CRISPRi). The loxp-stop-loxp cassette was deleted.

Mice

Wt1-CreERT2

Strain Name:C57BL/6Smoc-Wt1em1(CreERT2-WPRE-pA)Smoc
Strain State:Repository Live | Cat. NO.:NM-KI-200127

A CreERT2-WPRE-pA expression cassette was knocked into the Wt1 gene start codon site.

Mice

Il15-Luc-2A-EGFP

Strain Name:C57BL/6Smoc-Il15em1(Luc-eGFP)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KI-00027

A Luciferase-2A-EGFP-pA cassette was inserted after ATG the start codon. The intrisic promoter drives the expression of reporter genes, which reflects the activity of Il15.

Mice

Il7r-Cre

Strain Name:C57BL/6Smoc-Il7rem1(Cre-Wpre-pA)Smoc
Strain State:Repository Live | Cat. NO.:NM-KI-200306

Cre-Wpre-pA expression cassette was knocked into the Il7r gene start codon site.

Mice

Avp-IRES-Cre

Strain Name:C57BL/6Smoc-Avpem1(IRES2-Cre-WPRE-polyA)Smoc
Strain State:Repository Live | Cat. NO.:NM-KI-200142

A IRES2-Cre-WPRE-polyA expression cassette was knocked into the Avp gene stop codon site. Avp encodes arginine vasopressin. When crossed with a strain carrying a gene flanked by loxP sites, the flanked gene will be removed in cells expressing cre. This strain may be useful for studying hypertension.

Mice

Cd68-IRES-Cre

Strain Name:C57BL/6Smoc-Cd68em1(IRES-Cre)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KI-200161

A IRES-Cre expression cassette was knocked into the Cd68 gene stop codon site.

Mice

Slc34a1-CreERT2

Strain Name:C57BL/6Smoc-Slc34a1em1(CreERT2-SV40pA)Smoc
Strain State:Repository Live | Cat. NO.:NM-KI-210110

CreERT2-SV40pA expression cassette was knocked into the Slc34a1 gene .

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