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Models

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Mice

Isl1-CreERT2

Strain Name：C57BL/6Smoc-Isl1em1(CreERT2) Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-00013

CreERT2 was inserted at the start codon (ATG site). The KI mice have a tamoxifen-inducible cre-mediated recombination system.

Mice

Drd1-2A-CreERT2

Strain Name：C57BL/6Smoc-Drd1em1(2A-CreERT2-WPRE-pA)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-18016

A 2A-CreERT2-WPRE-pA coexpression cassette is inserted befor the stop codon of mouse Drd1 gene via homologous recombination to establish a tamoxifen inducible Drd1-CreERT2 tool stain. This strain can be used to knockout target gene in Drd1+ cells after tamoxifen treatment when crossed with mice which carry loxp sites flanking target gene.

Mice

Hopx-2A-DreERT2

Strain Name：C57BL/6Smoc-Hopxem1(2A-DreERT2)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-190035

A 2A-DreERT2 expression cassette was knocked into the Hopx gene stop codon site.

Mice

hCD3E(2)

Strain Name：C57BL/6Smoc-Cd3eem2(hCD3E)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-210023

The endogenous mice Cd3e gene was replaced by human CD3E gene. While hCD3E(Stock No.NM-HU-00114) mice function similarly to hCD3E(2) mice,for more detailed information please contact our technical advisor.

Mice

Trp63-DreERT2

Strain Name：C57BL/6Smoc-Trp63em1(DreERT2-Wpre-polyA)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-190029

A DreERT2-Wpre-polyA expression cassette was knocked into the exon4 of Trp63 gene.

Mice

H11-CAG-LSL-ZsGreen-CAG-RSR-tdTomato

Strain Name：C57BL/6Smoc-Igs2em1(CAG-LSL-ZsGreen-wpre-pA-CAG-RSR-tdTomato-wpre-pA)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200319

A CAG-LSL-ZsGreen-wpre-pA-CAG-RSR-tdTomato-wpre-pA expression cassette was knocked into the H11 locus.

Mice

hPD-L1/hSTING

Strain Name：C57BL/6Smoc-Tmem173tm1(hTMem173)Cd274em1(hCD274)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000105

hPD-L1(NM-HU-00062) was crossed with hSTING(NM-HU-190036) to generate hPD-L1/hSTING.

Mice

Rorc-2A-tdTomato-2A-DTR

Strain Name：C57BL/6Smoc-Rorcem(T2A-tdTomato-P2A-DTR)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-204991

T2A-tdTomato-P2A-DTR expression cassette was knocked into the Rorc gene .

Mice

Zbtb46-IRES-Cre

Strain Name：C57BL/6Smoc-Zbtb46em1(IRES-iCre)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200096

A  IRES-iCre expression cassette was knocked into the Zbtb46 gene stop codon site. This strain carries a significant risk of reproductive system leakage. Avoid using homozygotes and female Cre mice. It is recommended to use male mice, as they have a lower probability of leakage. After mating, offspring should be genotyped and promptly checked for any occurrence of reproductive leakage.

Mice

Ly6g-2A-CreERT2

Strain Name：C57BL/6Smoc-Ly6gem3(2A-CreERT2)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200218

A 2A-CreERT2 expression cassette was knocked into the Ly6g gene start codon site.

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