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Models

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Mice

Lgr5-EGFP-IRES-CreERT2

Strain Name:C57BL/6Smoc-Lgr5em1(EGFP-IRES-creERT2-WPRE-polyA)Smoc
Strain State:Repository Live | Cat. NO.:NM-KI-200154

A EGFP-IRES-creERT2-WPRE-polyA expression cassette was knocked into the Lgr5 gene start codon site.

Mice

Shh-EGFP-Cre

Strain Name:C57BL/6Smoc-Shhem1(EGFP-iCre)Smoc
Strain State:Repository Live | Cat. NO.:NM-KI-200232

A EGFP-iCre expression cassette was knocked into the Shh gene start codon site.

Mice

R26-CAG-LSL-hACE2-IRES-tdTomato

Strain Name:C57BL/6Smoc-Gt(ROSA)26Sorem1(SA-FRT-2xpolyA-CAG-FRT-Loxp-stop-loxp-human ACE2-IRES-tdTomato-WPRE-polyA)Smoc
Strain State:Repository Live | Cat. NO.:NM-KI-200188

These mice harbor a SA-FRT-2xpolyA-CAG-FRT-Loxp-stop-loxp-human ACE2-IRES-tdTomato-WPRE-polyAA cassette in the Rosa26 locus generated by homologous recombination.

Mice

Zbtb46-2A-CreERT2

Strain Name:C57BL/6Smoc-Zbtb46em1(2A-CreERT2-WPRE-pA)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KI-18021

A 2A-CreERT2-WPRE-pA coexpression cassette is inserted befor the stop codon of mouse Zbtb46 gene via homologous recombination to establish a tamoxifen inducible Zbtb46-CreERT2 tool stain. This strain can be used to knockout target gene in Zbtb46+ cells after tamoxifen treatment when crossed with mice which carry loxp sites flanking target gene.

Mice

hGLP1R

Strain Name:C57BL/6Smoc-Glp1rem2(hGLP1R)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-200220

The endogenous mouse Glp1r gene was completely or partially replaced by human hGLP1R gene via CRISPR/Cas9 mediated recombination.

Mice

Mefv-hMEFV*V726A

Strain Name:C57BL/6Smoc-Mefvem1(hMEFV-V726A)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KI-200221

Exon 7-10 of the endogenous mouse Mefv gene was replaced by human mutation gene (exon7-10).

Mice

Epcam-2A-CreERT2

Strain Name:C57BL/6Smoc-Epcamem1(2A-CreERT2)Smoc
Strain State:Repository Live | Cat. NO.:NM-KI-00084

An 2A-CreERT2 co-expression cassette is inserted before 3'UTR region of Epcam gene .

Mice

Cd19-Cre-IRES-tdTomato

Strain Name:C57BL/6Smoc-Cd19em1(iCre-FRT-IRES-tdTomato-FRT-Wpre-polyA)Smoc
Strain State:Repository Live | Cat. NO.:NM-KI-200061

A iCre-FRT-IRES-tdTomato-FRT-Wpre-polyA expression cassette was knocked into the Cd19 gene.

Mice

Pde6b-R560C (Rd10)

Strain Name:C57BL/6Smoc-Pde6bem1R560CSmoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KI-232201

These strains carry a R560C mutation of Pde6b gene.

Mice

Tigre-pTRE2-LSL-ZGX!EmGFP-2A-ZGX!TagGFP2-2A-ZGX!hrGFP-CAG-LSL-tTA2

Strain Name:C57BL/6Smoc-Igs7em1(2Xlns-pTRE2-Lox2272-stop-Lox2272-ZGX!emGFP-T2A-ZGX!TagGFP2-P2A-ZGX!hrGFP-Wpre-pA-2Xlns-pCAG-LoxP-stop-LoxP-tTA2-Wpre-pA)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KI-200288

A 2Xlns-pTRE2-Lox2272-stop-Lox2272-ZGX!EmGFP-T2A-ZGX!TagGFP2-P2A-ZGX!hrGFP- Wpre-pA-2Xlns-pCAG-LoxP-stop-LoxP-tTA2-Wpre-pA expression cassette was knocked into the TIGRE locus via CRISPR/Cas9 mediated recombination.

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