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Models

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Mice

Cd74-KO(2)

Strain Name:C57BL/6Smoc-Cd74em2Smoc
Strain State:Repository Live | Cat. NO.:NM-KO-200715

Cd74-KO(2) mice (Stock No.NM-KO-200715) carry a knockout allele derived from the targeted deletion of exon 2-3. While Cd74-KO mice (Stock No.NM-KO-190772) have been pulled from shelves for some reasons.

Mice

Cd74-KO

Strain Name:C57BL/6Smoc-Cd74em1Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KO-190772

Using CRISPR/Cas9 technology,exon 2 of Cd74 gene was deleted to generate Cd74 knockout mice.

Mice

Cd2-KO

Strain Name:C57BL/6Smoc-Cd2em1Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KO-191183

Exon 2-5 of Cd2 gene was deleted to generate Cd2 knockout mice.

Mice

Calm1-KO

Strain Name:C57BL/6Smoc-Calm1em1Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KO-190703

Exon 2 of Calm1 gene was deleted to generate Calm1 knockout mice.

Rats

M-SDR

Strain Name:SD-Rag2em1Smoc Strain State:Repository Live | Cat. NO.:NR-KO-190001

Exon 3 of Rag2 gene was deleted to generate Rag2 knockout rat.

Rats

Foxn1-KO(SD)

Strain Name:SD-Foxn1em1Smoc Strain State:Embryo cryopreservation | Cat. NO.:NR-KO-190002

Using CRISPR/Cas9 technology, Exon 2-4 of Foxn1 gene was deleted to generate Foxn1 knockout rat.

Rats

Ppara-KO(SD)

Strain Name:SD-Pparaem1Smoc Strain State:Repository Live | Cat. NO.:NR-KO-190004

Exon 4 of Ppara gene was deleted to generate Ppara knockout rat.

Literature
Pages

Workshop:Progress and Advances in Preclinical immuno-Oncology Research

SMOC’s Annual Progress and Advances in Preclinical immuno-Oncology Research: The workshop is designed as a forum for ideas and opinions exchange on how to decrease the rate of clinical failures in oncology and immuno-oncology.

Pages

Advancing Cancer Therapy: Harnessing In Vivo Tumor Models for Breakthrough Drug Development

Cancer therapy advancements In vivo tumor models Preclinical cancer research Drug development in oncology Gene-modified cell lines Immuno-oncology Tumor modeling for drug discovery Cancer drug development Animal modeling services Cancer drug preclinical models

Join us for an insightful webinar exploring the critical role of in vivo tumor models in advancing cancer drug therapy. We will provide an overview of the diverse tumor models developed by our company, highlighting case studies demonstrating their effectiveness in preclinical cancer research. The session will delve into the comprehensive use of gene-modified cell lines and genetically modified spontaneous mouse models, showcasing their application in mimicking human cancer biology. We will conclude with a brief introduction to our company and our commitment to accelerating cancer drug development through innovative animal modeling services.

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