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Models

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Rats

M-SDR

Strain Name:SD-Rag2em1Smoc Strain State:Repository Live | Cat. NO.:NR-KO-190001
Validation Data:Presence

Exon 3 of Rag2 gene was deleted to generate Rag2 knockout rat.

Rats

Foxn1-KO(SD)

Strain Name:SD-Foxn1em1Smoc Strain State:Embryo cryopreservation | Cat. NO.:NR-KO-190002

Using CRISPR/Cas9 technology, Exon 2-4 of Foxn1 gene was deleted to generate Foxn1 knockout rat.

Rats

Ppara-KO(SD)

Strain Name:SD-Pparaem1Smoc Strain State:Embryo cryopreservation | Cat. NO.:NR-KO-190004

Exon 4 of Ppara gene was deleted to generate Ppara knockout rat.

Literature
Pages

Workshop:Progress and Advances in Preclinical immuno-Oncology Research

SMOC’s Annual Progress and Advances in Preclinical immuno-Oncology Research: The workshop is designed as a forum for ideas and opinions exchange on how to decrease the rate of clinical failures in oncology and immuno-oncology.

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Advancing Cancer Therapy: Harnessing In Vivo Tumor Models for Breakthrough Drug Development

Cancer therapy advancements In vivo tumor models Preclinical cancer research Drug development in oncology Gene-modified cell lines Immuno-oncology Tumor modeling for drug discovery Cancer drug development Animal modeling services Cancer drug preclinical models

Join us for an insightful webinar exploring the critical role of in vivo tumor models in advancing cancer drug therapy. We will provide an overview of the diverse tumor models developed by our company, highlighting case studies demonstrating their effectiveness in preclinical cancer research. The session will delve into the comprehensive use of gene-modified cell lines and genetically modified spontaneous mouse models, showcasing their application in mimicking human cancer biology. We will conclude with a brief introduction to our company and our commitment to accelerating cancer drug development through innovative animal modeling services.

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Join Our Webinar: Applications of Humanized Mouse Models in Preclinical Research

Humanized mouse models preclinical research targeted therapies webinar oncology drug development preclinical therapeutic advancements immune system models animal modeling services

Join GenoBioTX's webinar on July 25th to explore the latest advancements in humanized mouse models for preclinical research. Learn how these models are transforming targeted therapy development across various diseases. Featuring expert insights from Dr. Derek Reznik, discover the generation and application of humanized immune system models in oncology drug development. Don't miss this opportunity to enhance your knowledge in cutting-edge preclinical therapeutic advancements. Register now!

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SMOC Launched U-HuDTMbase®, Inclusive Resource Library of Innovative Therapeutic Target-Humanized Mouse Models, to Accelerate Novel Drug Discovery

U-HuDTMbase® is composed of more than 600 therapeutic target-humanized mouse models, including multiple background strains, and has covered almost all commonly studied areas, such as oncology, metabolism, immunity, inflammation and more.

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