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Models

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Mice

hIL3

Strain Name：C57BL/6Smoc-Il3tm1(hIL3)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-190009

The endogenous mouse Il3 gene was replaced by human IL3 gene.

Mice

Il9-Luc-2A-EGFP

Strain Name：C57BL/6Smoc-Il9em1(Luc-eGFP)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-00023

A Luciferase-2A-EGFP-pA cassette was inserted after ATG the start codon. The intrisic promoter drives the expression of reporter genes, which reflects the activity of Il9.

Mice

MHC Class II(I-A/I-E)-KO(Nod-Scid)

Strain Name：NOD-PrkdcscidH2-Ab1em1H2-Aaem1H2-Eb1em1H2-Eb2em1H2-Ea-psem1Smoc
Strain State：Developing | Cat. NO.：NM-KO-18057

All sequences from the upstream of mouse H2-Ab1 gene exon 2 to the upstream of the H2-Ea-ps gene exon 1 were knocked out to obtain H2-Ab1、H2-Aa、H2-Eb1、H2-Eb2、H2-Ea-ps knockout mouse models. These MHC class II molecule-deficient mice were on the Nod-Scid genetic background and lacked cell surface expression of both class II-A and class II-E MHC proteins.

Mice

Fas-KO(BALB/c)

Strain Name：BALB/cAnSmoc-Fasem2Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-191206

Exon 2 of Fas gene was deleted to generate Fas knockout mice.

Mice

hSIRPA(2)/hCD47/hPD-1

Strain Name：C57BL/6Smoc-Sirpatm2(hSIRPA)Cd47tm1(hCD47) Pdcd1tm1(hPDCD1)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-HU-2000090

hPD-1(NM-HU-00015),hCD47(NM-HU-00050) were crossed with hSIRPA(2) (NM-HU-18015) to generate hSIRPA(2)/hCD47/hPD-1.

Mice

Prkn-KO

Strain Name：C57BL/6Smoc-Prknem1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-190335

Prkn-KO mice (Stock No.NM-KO-190335）carry a knockout allele derived from the targeted deletion of exon 3. While Prkn-KO(2) mice (Stock No.NM-KO-191005）mice carrying the exon 4 deletion.

Mice

Lgals3-KO

Strain Name：C57BL/6Smoc-Lgals3em1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-190107

This Lgals3 knockout mouse model was generated by knocking out the exon 3-4 region of the Lgals3 .

Mice

Prf1-KO

Strain Name：C57BL/6Smoc-Prf1em1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-190193

This Prf1 knockout mouse model was generated by knocking out the exon 3 region of the Prf1.

Mice

Des-KO

Strain Name：C57BL/6Smoc-Desem1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-190261

This Des knockout mouse model was generated by knocking out the exon 2-5 region of the Des.

Mice

Pd-1-KO

Strain Name：C57BL/6Smoc-Pdcd1em3Smoc
Strain State：Repository Live | Cat. NO.：NM-KO-190423
Validation Data：Presence

The Pdcd1 knockout mouse model was generated by knocking out the exon2-4 region of the Pdcd1.

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