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Models

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Mice

hIFNA1

Strain Name:C57BL/6Smoc-Ifna1tm(hIFNA1)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-220356
Validation Data:Presence

The endogenous mouse Ifna1 gene was replaced by human IFNA1 gene.

Mice

hAGT/hREN

Strain Name:C57BL/6Smoc-Agttm1(hAGT)Ren1tm(hREN)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-234349
Validation Data:Presence

The hREN(2)(NM-HU-220370) was crossed with hAGT(NM-HU-225082) to generate hAGT/hREN mice.

Mice

hNOTCH1

Strain Name:C57BL/6Smoc-Notch1tm(hNOTCH1)Smoc
Strain State:Developing | Cat. NO.:NM-HU-230038

The endogenous mouse Notch1 gene was replaced by human NOTCH1 gene.

Mice

hALDH2

Strain Name:C57BL/6Smoc-Aldh2tm1(hALDH2)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-231912

The endogenous mouse Aldh2 gene was replaced by human ALDH2 gene.

Mice

hMC4R-R165W

Strain Name:C57BL/6Smoc-Mc4rtm1(hMC4R-R165W)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-233884
Validation Data:Presence

The endogenous mouse Mc4r gene was replaced by hMC4R-R165W.

Mice

hIL18/hIL18BP

Strain Name:C57BL/6Smoc-Il18tm1(hIL18)Il18bptm1(hIL18BP)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-XA-234929

The hIL18BP(NM-HU-210039) was crossed with hIL18(NM-HU-210038) to generate hIL18/hIL18BP mice.

Mice

hCSF3(NMG)

Strain Name:NOD.Cg-PrkdcscidIl2rgem1Tg(hCSF3)Smoc
Strain State:Repository Live | Cat. NO.:NM-KI-232692
Validation Data:Presence

These transgenic mice harbor hCSF3 expression cassettes.

Mice

hIL6

Strain Name:C57BL/6Smoc-Il6tm1(hIL6)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-18017

This IL6 humanized mouse model was established by replacing the mouse Il6 gene coding exon1-5 and introns with the human IL6 corresponding sequence by homologous recombination via ES cell targeting.

Mice

hL1CAM

Strain Name:C57BL/6Smoc-L1camtm(hL1CAM)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-220414
Validation Data:Presence

The endogenous mouse L1cam gene was replaced by human L1CAM gene.

Mice

hCD28/hPD-1/hPD-L1

Strain Name:C57BL/6Smoc-Cd28tm2(hCD28)Pdcd1tm1(hPDCD1)Cd274tm1(hPD-L1)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-232307

The hPD-1/hPD-L1(NM-HU-00100) was crossed with hCD28(NM-HU-190011) to generate hCD28/hPD-1/hPD-L1 mice.

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