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Models

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Mice

hPD-1/hOX40

Strain Name:C57BL/6Smoc-Pdcd1tm1(hPDCD1)Tnfrsf4tm3(hTNFRSF4) Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-00108

hPD-1(NM-HU-00015)was crossed with hOX40(NM-HU-00041)to generate hPD-1/hOX40.

Mice

Hopx-2A-DreERT2

Strain Name:C57BL/6Smoc-Hopxem1(2A-DreERT2)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KI-190035
Validation Data:Presence  |  Publications:1piece

A 2A-DreERT2 expression cassette was knocked into the Hopx gene stop codon site.

Mice

hIL17F

Strain Name:C57BL/6Smoc-Il17ftm2(hIL17F)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-190007
Validation Data:Presence

The endogenous mouse Il17 gene was replaced by human IL17F gene.

Mice

hCD40L(BALB/c)

Strain Name:BALB/cAnSmoc-Cd40lgtm1(hCD40L)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-2000052

The endogenous mouse Cd40lg gene was replaced by human CD40L gene.

Mice

hIL4RA

Strain Name:C57BL/6Smoc-Il4ratm1(hIL4R)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-190008
Validation Data:Presence

The endogenous mouse Il4ra gene was replaced by human IL4R gene.

Mice

hIL4/hIL4R

Strain Name:C57BL/6Smoc-Il4tm3(hIL4)Il4ratm1(hIL4R)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-2000106
Validation Data:Presence

These mice are obtained through breeding of two single gene humanized mice.

Mice

hCYP2D6

Strain Name:C57BL/6Smoc-Cyp2dtm(hCYP2D6)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-HU-215024

The endogenous mouse Cyp2d22 gene was replaced by human CYP2D6 gene.

Mice

hTIGIT(3)

Strain Name:C57BL/6Smoc-Tigittm3(hTIGIT)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-200244
Validation Data:Presence

The endogenous mouse Tigit gene was replaced by human TIGIT gene. While hTIGIT(Stock No.NM-HU-00053) mice function similarly to hTIGIT(3) mice ,for more detailed information please contact our technical advisor.

Mice

hIL11RA

Strain Name:C57BL/6Smoc-Il11ra1tm1(hIL11RA)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-204982

The endogenous mice Il11ra1 gene was replaced by human IL11RA gene.

Mice

hTNFRSF10B

Strain Name:C57BL/6Smoc-Tnfrsf10btm1(hTNFRSF10B)/Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-210005

The endogenous mice Tnfrsf10B gene was replaced by human TNFRSF10B gene

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