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Models

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Mice

hCD22

Strain Name：C57BL/6Smoc-Cd22tm2(hCD22)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000014
Validation Data：Presence

The endogenous mouse Cd22 gene was replaced by human CD22 gene.

Mice

hCD3E(2)

Strain Name：C57BL/6Smoc-Cd3etm2(hCD3E)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-210023

The endogenous mice Cd3e gene was replaced by human CD3E gene. While hCD3E(Stock No.NM-HU-00114) mice function similarly to hCD3E(2) mice,for more detailed information please contact our technical advisor.

Mice

hCD47(Balb/c,2)

Strain Name：BALB/cAnSmoc-Cd47tm2(hCD47)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-210359
Validation Data：Presence

The endogenous mice Cd47 gene was replaced by human CD47 gene. While hCD47(BALB/c)(Stock No.NM-HU-2000022) mice function similarly to hCD47(BALB/c,2) mice, for more detailed information please contact our technical advisor.

Mice

hTIM3

Strain Name：C57BL/6Smoc-Havcr2tm1(hHAVCR2)/Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-00054
Validation Data：Presence

The endogenous mouse Tim3 gene was replaced by human TIM3 gene .

Mice

hHER2

Strain Name：C57BL/6Smoc-Erbb2tm1(hERBB2)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-200115
Validation Data：Presence

The endogenous mouse Erbb2 gene was replaced by human ERBB2 gene.

Mice

hIL17A/hIL17F

Strain Name：C57BL/6Smoc-Il17atm1(hIL17A)Il17fem2(hIL17F)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-200281
Validation Data：Presence

The endogenous mouse Il17a&Il17f genes were replaced by human IL17A&IL17F gene.

Mice

hFCRN(2)

Strain Name：C57BL/6Smoc-Fcgrttm2(hFCGRT)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-190070
Validation Data：Presence  |  Publications：1piece

The endogenous mouse Fcgrt gene was replaced by human FCGRT gene.While hFCRN(Stock No.NM-HU-00109) and hFCRN(3)(Stock No.NM-HU-2000032）mice function similarly to hFCRN(2) mice,for more detailed information please contact our technical advisor.

Mice

hIFNGR1

Strain Name：C57BL/6Smoc-Ifngr1tm(hIFNGR1)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-190076
Validation Data：Presence

The endogenous mouse Ifngr1 gene was replaced by human IFNGR1 gene.

Mice

H11-CAG-RSR-EYFP

Strain Name：C57BL/6Smoc-Igs2em1(CAG-RSR-EYFP)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-18056

A CAG-ROX-STOP-ROX-EYFP-V5tag-polyA conditional expression cassette was knocked into the Igs2 locus (Hipp11 or H11; an intergenic region on chromosome 11 [cytoband A1 at ~3cM between the Eif4enif1 and Drg1 loci] reported to support high-level global gene expression in conjunction with the CAG (CAGGS) promoter and a higher rate of mitotic/interchromosomal recombination compared to Gt(ROSA)26Sor) . This strain of mice can be used to mate with mice expressing the Dre recombinase. After exposure to Dre recombinase, expression of ellow fluorescent protein and V5 tag is observed for cell tracking.

Mice

hPVR

Strain Name：C57BL/6Smoc-Pvrtm1(hPVR)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-190012
Validation Data：Presence

The endogenous mouse Pvr gene was replaced by human PVR gene.

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