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Mice

Clec4f-IRES-DTRGFP

Strain Name：C57BL/6Smoc-Clec4fem1(IRES-DTRGFP)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-200070

A IRES-DTRGFP expression cassette was knocked into the Clec4f gene stop codon site.

Mice

Gsk3b-Flox

Strain Name：C57BL/6Smoc-Gsk3bem1(flox)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-CKO-200098

These mice carry loxP sites flanking exon 2 of Gsk3b gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Gsk3b gene.

Mice

Stag2-Flox

Strain Name：C57BL/6Smoc-Stag2tm1(flox)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-CKO-200138

These mice carry loxP sites flanking exon 7 of Stag2 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Stag2 gene.

Mice

Glp1r-IRES-Cre

Strain Name：C57BL/6Smoc-Glp1rem1(IRES-iCre)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200134

A IRES-iCre expression cassette was knocked into the Glp1r gene stop codon site.

Mice

Il17a-Cre

Strain Name：C57BL/6Smoc-Il17aem1(iCre-polyA(SV40))Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-200137

A iCre-polyA expression cassette was knocked into the Il17a gene start codon site. This gene encodes a pro-inflammatory cytokine that is a member of the interleukin-17 family. When crossed with a strain carrying a gene flanked by loxP sites, the flanked gene will be removed in cells expressing cre. This strain may be useful for studying autoimmune inflammatory diseases such as rheumatoid arthritis, psoriasis and multiple sclerosis.

Mice

Nbn-Flox

Strain Name：C57BL/6Smoc-Nbnem1(flox)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-CKO-241068

These strains carry loxP sites flanking exon 6 of Nbn gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Nbn gene.

Mice

Foxn1-IRES-Cre

Strain Name：C57BL/6Smoc-Foxn1em1(IRES-iCre)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-200106

A IRES-iCre expression cassette was knocked into the Foxn1 gene stop codon site. The protein encoded by Foxn1 (forkhead box N1) gene is part of the forkhead family or transcription factors that are important in developmental processes, immune system regulation, metabolism, cancer and aging. When crossed with a strain carrying a gene flanked by sites, the flanked gene will be removed in thymic epithelial cell and keratinocytes.

Mice

Rictor-Flox

Strain Name：C57BL/6Smoc-Rictorem1(flox)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-CKO-200214

These mice carry loxP sites flanking exon 11 of Rictor gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Rictor gene.

Mice

Sox9-IRES-CreERT2

Strain Name：C57BL/6Smoc-Sox9em(IRES-CreERT2-SV40pA)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-204996

IRES-CreERT2-SV40pA expression cassette was knocked into the Sox9 gene .

Mice

Prom1-CreERT2

Strain Name：C57BL/6Smoc-Prom1em1(CreERT2-PolyA)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200169

A CreERT2-PolyA expression cassette was knocked into the Prom1 gene start codon site. Prom1 encodes a pentaspan transmembrane glycoprotein. The protein localizes to membrane protrusions and is often expressed on adult stem cells, where it is thought to function in maintaining stem cell properties by suppressing differentiation. When these Prom1-CreERT2 mice are bred with mice containing a loxP-flanked sequence of interest, tamoxifen-inducible, Cre-mediated recombination will result in deletion of the flanked sequences in Prom1 expressing cells.

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