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Mice

Dicer1-Flox

Strain Name：C57BL/6Smoc-Dicer1em1(flox)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-CKO-200158

These mice carry loxP sites flanking exon 23 of Dicer1 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Dicer1 gene.

Mice

Prom1-CreERT2

Strain Name：C57BL/6Smoc-Prom1em1(CreERT2-PolyA)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-200169
Validation Data：Presence

A CreERT2-PolyA expression cassette was knocked into the Prom1 gene start codon site. Prom1 encodes a pentaspan transmembrane glycoprotein. The protein localizes to membrane protrusions and is often expressed on adult stem cells, where it is thought to function in maintaining stem cell properties by suppressing differentiation. When these Prom1-CreERT2 mice are bred with mice containing a loxP-flanked sequence of interest, tamoxifen-inducible, Cre-mediated recombination will result in deletion of the flanked sequences in Prom1 expressing cells.

Mice

Il13-IRES-Cre

Strain Name：C57BL/6Smoc-Il13em1(IRES-iCre)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-200166
Validation Data：Presence

A IRES-iCre expression cassette was knocked into the Il13 gene stop codon site. This gene encodes a multifunctional cytokine. When crossed with a strain carrying a gene flanked by loxP sites, the flanked gene will be removed in cells expressing cre. This cytokine participates in the regulation of immune response, inflammatory response and hematopoietic process.

Mice

Smad4-Flox

Strain Name：C57BL/6Smoc-Smad4tm1(flox)Smoc
Strain State：Repository Live | Cat. NO.：NM-CKO-18011

These mice carry loxP sites flanking exon3-4 of Smad4 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Smad4 gene.

Mice

Kit-V831M(NOD-scid)

Strain Name：NOD-PrkdcscidKitem1(V831M)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-200316

These NOD-scid mice carry a p.V831M mutation of Kit gene.

Mice

Nf2-Flox

Strain Name：C57BL/6Smoc-Nf2tm1(flox)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-CKO-200017

These mice carry loxP sites flanking exon 2 of Nf2 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Nf2 gene.

Mice

Csf1r-Flox

Strain Name：C57BL/6Smoc-Csf1rem1(flox)Smoc
Strain State：Repository Live | Cat. NO.：NM-CKO-200091

These mice carry loxP sites flanking exon 5 of Csf1r gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Csf1r gene.

Mice

Hdac9-Flox

Strain Name：C57BL/6Smoc-Hdac9em1(flox)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-CKO-00125

These mice carry loxP sites flanking exon 3 of HDAC9 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of this gene.

Mice

Il22ra1-Flox

Strain Name：C57BL/6Smoc-Il22ra1em1(flox)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-CKO-200106

These mice carry loxP sites flanking exon 3 of Il22ra1 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Il22ra1 gene.

Mice

Gja1-Flox

Strain Name：C57BL/6Smoc-Gja1em1(flox)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-CKO-200180

These mice carry loxP sites flanking exon 2 of Gja1 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Gja1 gene.

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